Results 21 to 30 of about 45,869 (242)
Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis [PDF]
, 2018 Objective: Mavrilimumab, a human monoclonal antibody, targets granulocyte-macrophage colony-stimulating factor receptor alpha. We report mavrilimumab long-term safety and efficacy in rheumatoid arthritis patients in two phase IIb studies (1071, 1107 ...
Achuthan +44 more
core +1 more source
Protective effect of thymoquinone against lung intoxication induced by malathion inhalation
Scientific Reports, 2021 Malathion is considered one of the vastest pesticides use all over the world. Malathion-inhalation toxicity commonly occurred in many occupational farmers.
Walied Abdo +7 more
doaj +1 more source
Therapeutic Advances in Respiratory Disease, 2016 Background: The aim of this study was to determine the influence of selected physiological, psychological and situational factors on experience of fatigue, and functional limitations due to fatigue in patients with stable chronic obstructive pulmonary ...
Magnus Kentson +6 more
doaj +1 more source
Egyptian Journal of Chest Disease and Tuberculosis, 2016 Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects approximately 1% of the population, and pulmonary involvement is common.
Ashraf E. Sileem +3 more
doaj +1 more source
Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations [PDF]
, 2014 BACKGROUND: Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis (IPF) have focused on resequencing single genes in IPF kindreds or cohorts to determine the genetic contributions to IPF.
Coghlan, Meghan A +8 more
core +3 more sources
Surfactant function in neonates with respiratory distress syndrome [PDF]
, 1998 The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was ...
Griese, Matthias, Westerburg, Bettina
core +1 more source
The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants [PDF]
, 2018 Inhaled nanoparticles traveling through the airways are able to reach the respiratory zone of the lungs. In such event, the incoming particles first enter in contact with the liquid lining the alveolar epithelium, the pulmonary surfactant.
Berret, J. -F., Mousseau, F.
core +4 more sources
Multifunctional nanocarriers for lung drug delivery [PDF]
, 2020 Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core +2 more sources
Surfactant Protein D in Respiratory and Non-Respiratory Diseases
Frontiers in Medicine, 2018 Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune defense and expressed in pulmonary, as well as non-pulmonary, epithelia.
Grith L. Sorensen
doaj +1 more source
Respiratory Research, 2008 Background Surfactant protein D (SP-D), an innate immune molecule, plays an important protective role during airway inflammation. Deficiency of this molecule induces emphysematous changes in murine lungs, but its significance in human COPD remains ...
Beers Michael F +6 more
doaj +1 more source