Results 41 to 50 of about 73,726 (337)

A finite membrane element formulation for surfactants

, 2019
Surfactants play an important role in various physiological and biomechanical applications. An example is the respiratory system, where pulmonary surfactants facilitate the breathing and reduce the possibility of airway blocking by lowering the surface ...
Roohbakhshan, Farshad, Sauer, Roger A.
core   +1 more source

Lung Surfactant Lipids Provide Immune Protection Against Haemophilus influenzae Respiratory Infection

Frontiers in Immunology, 2019
Non-typeable Haemophilus influenzae (NTHi) causes persistent respiratory infections in patients with chronic obstructive pulmonary disease (COPD), probably linked to its capacity to invade and reside within pneumocytes.
Belén García-Fojeda, Belén García-Fojeda, Zoe González-Carnicero, Alba de Lorenzo, Carlos M. Minutti, Carlos M. Minutti, Lidia de Tapia, Begoña Euba, Begoña Euba, Alba Iglesias-Ceacero, Sonia Castillo-Lluva, Junkal Garmendia, Junkal Garmendia, Cristina Casals, Cristina Casals   +14 more
doaj   +1 more source

Genetic risk factors associated with respiratory distress syndrome [PDF]

Korean Journal of Pediatrics, 2014
Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect the development of RDS.
Heui Seung Jo
doaj   +1 more source

Surfactant Treatment Shows Higher Correlation Between Ventilator and EIT Tidal Volumes in an RDS Animal Model

Frontiers in Physiology, 2022
Neonatal respiratory distress syndrome (RDS) is a condition of pulmonary surfactant insufficiency in the premature newborn. As such, artificial pulmonary surfactant administration is a key treatment. Despite continued improvement in the clinical outcomes
Yoon Zi Kim, Hee Yoon Choi, Yong Sung Choi, Chae Young Kim, Young Joo Lee, Sung Hoon Chung   +5 more
doaj   +1 more source

The biophysical function of pulmonary surfactant [PDF]

Respiratory Physiology & Neurobiology, 2008
Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two key aspects of this function: that the surfactant film forms rapidly; and that when compressed by the shrinking alveolar area during exhalation, the film reduces surface tension to very low values.
Sandra Rugonyi, Stephen B. Hall, Samares C. Biswas   +2 more
openaire   +3 more sources

The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry

Journal of Nanobiotechnology, 2010
Background During production and processing of multi-walled carbon nanotubes (MWCNTs), they may be inhaled and may enter the pulmonary circulation. It is essential that interactions with involved body fluids like the pulmonary surfactant, the blood and ...
Yan Bing, Nelle Mathias, Gehr Peter, Krug Harald F, Rothen-Rutishauser Barbara, Gasser Michael, Wick Peter   +6 more
doaj   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Patterns of recruitment and injury in a heterogeneous airway network model [PDF]

, 2015
In respiratory distress, lung airways become flooded with liquid and may collapse due to surface-tension forces acting on air-liquid interfaces, inhibiting gas exchange.
Cressoni M, Murphy SL, Oliver E. Jensen, Peter S. Stewart, The Acute Respiratory Distress Syndrome Network, Weibel ER   +5 more
core   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, Volume 35, Issue 35, August 28, 2025.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

The role of miR-431-5p in regulating pulmonary surfactant expression in vitro

Cellular & Molecular Biology Letters, 2019
Background Pulmonary surfactant is the complex mixture of lipid and protein that covers the alveolar surface. Pulmonary surfactant deficiency is one of the main causes of neonatal respiratory distress.
Shujun Li, Zhongyi Sun, Tao Chen, Jingjing Pan, Yanqing Shen, Xiaoqing Chen, Xiaoyu Zhou, Rui Cheng, Yang Yang   +8 more
doaj   +1 more source