Results 41 to 50 of about 1,404,214 (346)

A finite membrane element formulation for surfactants

, 2019
Surfactants play an important role in various physiological and biomechanical applications. An example is the respiratory system, where pulmonary surfactants facilitate the breathing and reduce the possibility of airway blocking by lowering the surface ...
Roohbakhshan, Farshad, Sauer, Roger A.
core   +1 more source

Engineering novel complement activity into a pulmonary surfactant protein [PDF]

, 2010
Complement neutralizes invading pathogens, stimulates inflammatory and adaptive immune responses, and targets non- or altered-self structures for clearance.
Anthony H. Keeble, Brodsky-Doyle, Chen, Chen, Christopher Furze, Daniel A. Mitchell, Doliana, Emsley, Fan, Feinberg, Girija, Haurum, Heise, Hohenester, Hoppe, Jensenius, Julia Toth, Kaufman, Kurata, Phillips, Porter, Reid, Reid, Reid, Russell Wallis, Scherer, Shoulders, Sim, Strang, Teillet, Uemura, Umakhanth Venkatraman Girija, Wallis, Wallis, Wallis, Wallis, Wallis, Wallis, Wilhelm J. Schwaeble   +38 more
core   +2 more sources

Lung Surfactant Lipids Provide Immune Protection Against Haemophilus influenzae Respiratory Infection

Frontiers in Immunology, 2019
Non-typeable Haemophilus influenzae (NTHi) causes persistent respiratory infections in patients with chronic obstructive pulmonary disease (COPD), probably linked to its capacity to invade and reside within pneumocytes.
Belén García-Fojeda, Belén García-Fojeda, Zoe González-Carnicero, Alba de Lorenzo, Carlos M. Minutti, Carlos M. Minutti, Lidia de Tapia, Begoña Euba, Begoña Euba, Alba Iglesias-Ceacero, Sonia Castillo-Lluva, Junkal Garmendia, Junkal Garmendia, Cristina Casals, Cristina Casals   +14 more
doaj   +1 more source

Biosynthesis of phosphatidylcholine by human lysophosphatidylcholine acyltransferase 11

Journal of Lipid Research, 2009
Pulmonary surfactant is a complex of phospholipids and proteins lining the alveolar walls of the lung. It reduces surface tension in the alveoli, and is critical for normal respiration.
Takeshi Harayama, Hideo Shindou, Takao Shimizu   +2 more
doaj   +1 more source

Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials

Small Science, 2021
The interplay of particles with pulmonary surfactant, a lipid‐protein material pivotal for lung function, is hypothesized as a key factor that has not been routinely considered in the current in vitro models when determining the fate of inhaled ...
Benedikt Huck, Alberto Hidalgo, Franziska Waldow, Dominik Schwudke, Karoline I. Gaede, Claus Feldmann, Patrick Carius, Chiara Autilio, Jesus Pérez-Gil, Konrad Schwarzkopf, Xabier Murgia, Brigitta Loretz, Claus-Michael Lehr   +12 more
doaj   +1 more source

Surfactant Treatment Shows Higher Correlation Between Ventilator and EIT Tidal Volumes in an RDS Animal Model

Frontiers in Physiology, 2022
Neonatal respiratory distress syndrome (RDS) is a condition of pulmonary surfactant insufficiency in the premature newborn. As such, artificial pulmonary surfactant administration is a key treatment. Despite continued improvement in the clinical outcomes
Yoon Zi Kim, Hee Yoon Choi, Yong Sung Choi, Chae Young Kim, Young Joo Lee, Sung Hoon Chung   +5 more
doaj   +1 more source

ABCG1 regulates pulmonary surfactant metabolism in mice and men[S]

Journal of Lipid Research, 2017
Idiopathic pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of surfactant. Surfactant synthesis and secretion are restricted to epithelial type 2 (T2) pneumocytes (also called T2 cells). Clearance of surfactant is
Thomas Q. de Aguiar Vallim, Elinor Lee, D. Merriott, C. Goulbourne, Joan Cheng, Angela Cheng, A. Gonen, Ryan M. Allen, E. Palladino, D. Ford, Tisha Wang, Á. Baldán, E. Tarling   +12 more
semanticscholar   +1 more source

Genetic risk factors associated with respiratory distress syndrome [PDF]

Korean Journal of Pediatrics, 2014
Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect the development of RDS.
Heui Seung Jo
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry

Journal of Nanobiotechnology, 2010
Background During production and processing of multi-walled carbon nanotubes (MWCNTs), they may be inhaled and may enter the pulmonary circulation. It is essential that interactions with involved body fluids like the pulmonary surfactant, the blood and ...
Yan Bing, Nelle Mathias, Gehr Peter, Krug Harald F, Rothen-Rutishauser Barbara, Gasser Michael, Wick Peter   +6 more
doaj   +1 more source