Results 91 to 100 of about 1,493,409 (315)
RHEOLOGICAL PROPERTIES OF SYNTHESIZED SURFACTANTS [PDF]
, 2005 Surfactants are surface-active substances of complex lipids. In nature, surfactants are substances consisting of lipoprotein that is secreted by the alveolar cells of the lung and serves to maintain the stability of pulmonary tissue by reducing the ...
SAMSUDIN, SHAHROL HAIRY
core
Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet +10 more
wiley +1 more source
Persistent pulmonary hypertension of the newborn
Journal of the Formosan Medical Association, 2013 Persistent pulmonary hypertension of the newborn (PPHN) is a severe pulmonary disorder which occurs at a rate of one in every 500 live births. About 10–50% of the victims will die of the problem and 7–20% of the survivors develop long-term impairments ...
Ru-Jeng Teng, Tzong-Jin Wu
doaj +1 more source
The Pulmonary Surfactant System
, 1994 The pulmonary surfactant system includes specific proteins involved in the regulation of surfactant secretion and recycling, conversion of secreted lamellar bodies to tubular myelin, film adsorption, and stimulation of alveolar macrophages.
JJ Batenburg, B Robertson, LMG van Golde
core +1 more source
Pulmonary surfactant in newborn infants and children
Breathe, 2013 Educational aims To understand the composition, secretory pathways and functions of pulmonary surfactant. To review the clinical evidence regarding the use of surfactants in newborn infants and children.
M. Chakraborty, S. Kotecha
semanticscholar +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
Drug Design, Development and Therapy, 2013 Johann M van Zyl,1 Johan Smith,2 Arthur Hawtrey1 1Division of Pharmacology, 2Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa Background: Currently, a new generation of synthetic pulmonary surfactants is being ...
van Zyl JM, Smith J, Hawtrey A
doaj
Interfacial structure of pulmonary surfactants revisited: Cholesterol and surface pressure effects. [PDF]
Biophys J, 2022 Nylander T.
europepmc +1 more source
Delivery and performance of surfactant replacement therapies to treat pulmonary disorders
Therapeutic delivery, 2013 Lung surfactant is crucial for optimal pulmonary function throughout life. An absence or deficiency of surfactant can affect the surfactant pool leading to respiratory distress.
N. El-gendy +3 more
semanticscholar +1 more source
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source