Results 121 to 130 of about 23,810 (346)

Potential Therapeutic Applications of Pulmonary Surfactant Lipids in the Host Defence Against Respiratory Viral Infections [PDF]

open access: gold, 2021
Jianjian Ji   +7 more
openalex   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu   +6 more
wiley   +1 more source

Machine Learning‐Driven Digital Twin of a Field‐Effect Transistor‐Based Hormone Biosensor for Real‐Time Estradiol Monitoring

open access: yesAdvanced Intelligent Systems, EarlyView.
A machine learning‐driven digital twin simulates an aptamer‐functionalized BioFET measuring 17β‐estradiol. Real‐time Isd signals are processed, features are extracted, and trained models estimate hormone concentration. In parallel, a one‐step‐ahead forward model learns biosensor dynamics and generates realistic synthetic signals, enabling in silico ...
Anastasiia Gorelova   +4 more
wiley   +1 more source

Animal poisonings in Belgium: a review of the past decade [PDF]

open access: yes, 2010
This review focuses on poisonings in companion animals, including horses, farm animals and wildlife, investigated and recorded during the past ten years at the Laboratory of Toxicology of the Faculty of Veterinary Medicine (Ghent University) and the ...
Croubels, Siska   +3 more
core   +1 more source

Long-term pulmonary sequence in surfactant treated preterm infants at school-age 87 [PDF]

open access: bronze, 1996
Monika Gappa   +4 more
openalex   +1 more source

N,N,N-Trimethyl chitosan as a permeation enhancer for inhalation drug delivery: Interaction with a model pulmonary surfactant [PDF]

open access: green, 2023
Jana Szabová   +5 more
openalex   +1 more source

An Evaluation of Mortality Rates and Their Determinants in a Cohort of Former Asbestos Miners in South Africa

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background A causal association between occupational asbestos exposure and lung disease, including pneumoconiosis and mesothelioma, is well established. Elevated mortality among former asbestos miners is expected. However, large‐scale South African studies examining all‐cause mortality in this population are lacking.
Yumna Williams‐Mohamed   +3 more
wiley   +1 more source

Pulmonary surfactant and drug delivery: Vehiculization, release and targeting of surfactant/tacrolimus formulations

open access: green, 2020
Alberto Hidalgo   +9 more
openalex   +2 more sources

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