Results 191 to 200 of about 350,037 (355)

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Diagnostic potential of WNT signaling gene methylation in pulmonary tuberculosis. [PDF]

Front Immunol
Wang H, Wang CC, Huang Q, Xiao Y, Han Y, Xie L, Liu Y, Xiong YJ.   +7 more
europepmc   +1 more source

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, EarlyView.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source

Pulmonary tuberculosis in diabetes: Exploring the intersection and impact on mental health. [PDF]

World J Clin Cases
Verma AK, Vats Y, Bajpai J, Kar SK, Pradhan A, Kant S.   +5 more
europepmc   +1 more source

CCR2 recruits monocytes to the lung, while CX3CR1 modulates positioning of CD11c ^pos cells in the lymph node during pulmonary tuberculosis

Alexander Mohapatra, Brian A. Norris, Zachary Howard, J. Ernst   +3 more
openalex   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

Immunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima, Ricardo C. Castro, Francisco R. Javier, Caroline Fontanari, Valdes R. Bollela, Rogerio S. Rosada, Célio L. Silva, Lúcia H. Faccioli, Luiz G. Gardinassi, Fabiani G. Frantz   +9 more
wiley   +1 more source

Effect of Isoniazid Resistance on Treatment Outcome Among People With Pulmonary Tuberculosis in Korea. [PDF]

J Korean Med Sci
Lee JM, Kim HW, Lee EG, Park Y, Jung SS, Kim JW, Oh JY, Lee H, Kim SH, Kim SH, Lyu J, Kwon SJ, Jeong YJ, Kim D, Koo HK, Chae G, Kyung SY, Lee SS, Park JS, Kim JS, Min J.   +20 more
europepmc   +1 more source

Research progress on lung cancer complicated with pulmonary tuberculosis: a narrative review

Zejun Zhou, Hai‐Yan Xie, Luca Bertolaccini, Ning Xia, Yu Zhang   +4 more
openalex   +1 more source

Initial Presentations Predict Mortality in Pulmonary Tuberculosis Patients - A Prospective Observational Study

, 2011
Jia-Yih Feng, W. Su, Yu-Chi Chiu, Shiang‐Fen Huang, Yung Yang Lin, Ruay-Ming Huang, Ching‐Hsiung Lin, Jhi-Jhu Hwang, Jen Jyh Lee, Ming-Chih Yu, Kwok Woon Yu, Yu Chin Lee   +11 more
openalex   +2 more sources

Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick, Alan D. Irvine, Jonathan I. Silverberg, Emma Guttman‐Yassky, Mona Shahriari, Xinghua Gao, Stephan Weidinger, Norito Katoh, Namita Vigna, Deanne M. Dilley, Elvira D'Andrea, Henrique D. Teixeira, Andrew M. Platt, Gweneth F. Levy   +13 more
wiley   +1 more source