Results 1 to 10 of about 1,287,782 (264)
Drug resistance in Plasmodium [PDF]
Nature Reviews Microbiology, 2018 A marked decrease in malaria-related deaths worldwide has been attributed to the administration of effective antimalarials against Plasmodium falciparum, in particular, artemisinin-based combination therapies (ACTs). Increasingly, ACTs are also used to treat Plasmodium vivax, the second major human malaria parasite.
Kasturi Haldar +2 more
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International Journal of Oncology, 1996 An overview of the current mechanisms identified as associated with the expression of multidrug resistance is provided. The clinical relevance of multidrug resistance associated with the overexpression of the three major drug resistance-associated proteins namely, P-glycoprotein, MRP and/or LRP, is discussed.
Giaccone, G., Pinedo, H.M.
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Microbiology Spectrum, 2023 With the application of bedaquiline (Bdq), the success rate of multidrug-resistant tuberculosis (MDR-TB) treatment has been significantly improved; however, the cardiac safety of the patients during treatment cannot be ignored. Hence, this study compared
Rong Li +6 more
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Introduction: Drug Resistance [PDF]
Chemical Reviews, 2021 Neşe Kurt Yilmaz, Celia A Schiffer
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A Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections
Vaccines, 2023 Antibody Dependent Enhancement (ADE) of an infection has been of interest in the investigation of many viruses. It is associated with the severity of the infection.
Jyoti Sawant, Ajit Patil, Swarali Kurle
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BMC Infectious Diseases, 2023 Background The World Health Organization has reported that the treatment success rate of multi-drug resistance tuberculosis is approximately 57% globally. Although new drugs such as bedaquiline and linezolid is likely improve the treatment outcome, there
J-B Ma +9 more
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Experimental Closed-Loop Control of Breast Cancer in Mice
Complexity, 2022 Cancer therapy optimization is an issue that can be solved using the control engineering approach. An optimal therapy generation algorithm is presented and tested using a tractable mouse model of breast cancer.
Levente Kovács +7 more
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mSystems, 2021 Accurate and timely functional genome annotation is essential for translating basic pathogen research into clinically impactful advances. Here, through literature curation and structure-function inference, we systematically update the functional genome ...
Samuel J. Modlin +10 more
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Burden of malaria infection among individuals of varied blood groups in Kenya
Malaria Journal, 2022 Background The ABO blood groups consist of A, B, and H carbohydrate antigens, which regulate protein activities during malaria infection in humans.
Redemptah Yeda +17 more
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Drug Resistance in Leishmaniasis [PDF]
Journal of Global Infectious Diseases, 2010 The treatment options of leishmaniasis are limited and far from satisfactory. For more than 60 years, treatment of leishmaniasis has centered around pentavalent antimonials (Sb(v)). Widespread misuse has led to the emergence of Sb(v) resistance in the hyperendemic areas of North Bihar. Other antileishmanials could also face the same fate, especially in
Jaya Chakravarty, Shyam Sundar
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