Results 51 to 60 of about 350,037 (355)

Host-directed therapy against mycobacterium tuberculosis infections with diabetes mellitus

Frontiers in Immunology
Tuberculosis (TB) is caused by the bacterial pathogen Mycobacterium tuberculosis (MTB) and is one of the principal reasons for mortality and morbidity worldwide.
Li Zhao, Ke Fan, Xuezhi Sun, Wei Li, Fenfen Qin, Liwen Shi, Feng Gao, Chunlan Zheng   +7 more
doaj   +1 more source

Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12) [PDF]

, 2015
Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Abbasi, A., Ghasemi Kebria, F., Hashemi Fard, A., Khodabakhshi, B., Khosravian, M.   +4 more
core  

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Use of low-dose computed tomography to assess pulmonary tuberculosis among healthcare workers in a tuberculosis hospital [PDF]

, 2017
BACKGROUND: According to the World Health Organization, China is one of 22 countries with serious tuberculosis (TB) infections and one of the 27 countries with serious multidrug-resistant TB strains.
Chen, Bu-Dong, He, Wei, Li, Cheng-Hai, Lv, Ping-Xin, Lv, Yan, Ning, Feng-Gang, Wang, Dong-Po, Xu, Jin-Ping, Zheng, Jie, Zhou, Xin-Hua, Zhou, Zhen   +10 more
core   +2 more sources

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Optimized anti-tuberculosis duration for drug-susceptible pulmonary tuberculosis-diabetes mellitus comorbidities: study protocol for a multicenter randomized controlled trial

BMC Pulmonary Medicine
Background The coexistence of tuberculosis (TB) and type 2 diabetes mellitus (DM) presents unique challenges in treatment optimization and management, given the mutual exacerbation of disease processes.
Peize Zhang, Huaifang Shi, Yongping Xie, Jiemei Liang, Qiumeng Hu, Liang Fu, Yuxiang Wang, Jie Tan, Senlin Zhan, Hongjuan Qin, Guanghui Xu, Guofang Deng   +11 more
doaj   +1 more source

Evaluation of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells for discrimination of active tuberculosis

BMC Infectious Diseases, 2022
Background Active tuberculosis (ATB) originates from primary Mycobacterium tuberculosis (MTB) infection or reactivation of latent tuberculosis. Besides bacteriological examination, MTB-reactive immunocytes detection can be an alternative testing for ...
Yong Fang, Na Wang, Liang Tang, Xiao-Jun Yang, Yuan Tang, Lin Li, Wen-Fei Wu, Bo Su, Wei Sha   +8 more
doaj   +1 more source

Performance of Nucleic Acid Amplification Tests in Patients with Presumptive Pulmonary Tuberculosis in Taiwan [PDF]

, 2022
Wei‐Chang Huang, Chih‐Bin Lin, Shun-Tien Chien, Jann‐Yuan Wang, Chou-Jui Lin, Jia‐Yih Feng, Chih‐Hsin Lee, Chin‐Chung Shu, Ming-Chih Yu, Jen‐Jyh Lee, Chen‐Yuan Chiang   +10 more
openalex   +1 more source

Hypercalcemia in Pulmonary Tuberculosis

Upsala Journal of Medical Sciences, 1990
Tuberculosis can affect calcium metabolism, mainly through an enhanced production of active vitamin D. The incidence of hypercalcemia among unselected patients with active pulmonary tuberculosis was investigated, retrospectively, during a ten-year period.
L, Lind, S, Ljunghall
openaire   +2 more sources

Diagnostics for pulmonary tuberculosis [PDF]

Postgraduate Medical Journal, 2016
AbstractTuberculosis (TB) remains a leading cause of human suffering and mortality despite decades of effective treatment being available. Accurate and timely diagnosis remains an unmet goal. The HIV epidemic has also led to new challenges in the diagnosis of TB.
Patrick Cudahy, Sheela V Shenoi
openaire   +2 more sources