Results 101 to 110 of about 236,945 (306)

A randomized comparison of cryoballoon versus duty-cycled multielectrode radiofrequency ablation for pulmonary vein isolation

, 2014
Cryoballoon (CB) and multipolar phased radiofrequency (RF) ablation with the Pulmonary Vein Ablation Catheter (PVAC) have been introduced as a faster and simpler procedure for pulmonary vein isolation (PVI).
Lenz, Anna Christina
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease

, 2008
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Jian Zhuang, Hongsui Wu, Shiliang Chen, Jian Su, Yuhui Zheng, Xiaoning Zhang, Jianguang Chen, Huanxin Yang, Zhihong Chen   +8 more
core  

Structural features of the pulmonary vein and left atrial diameter.

, 2014
NOTE: PV, pulmonary vein; LSPV, left superior pulmonary vein; LIPV, left inferior pulmonary vein; RSPV, right superior pulmonary vein; RIPV, right inferior pulmonary vein; OLPV, overall left pulmonary vein; ORPV, overall right pulmonary vein; OSPV ...
Xue-Bo Liu (547571), Jun-Bo Ge (547569), Li Lin (111038), Yu Zou (547570), Ying Cai (22305), Wei Wei (21173), Wen-Qing Zhu (547572)   +6 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Involvement of the Na+/Ca2+ Exchanger in the Automaticity of Guinea-Pig Pulmonary Vein Myocardium as Revealed by SEA0400

Journal of Pharmacological Sciences, 2009
.: We examined the involvement of the Na+/Ca2+ exchanger in the automaticity of the pulmonary vein myocardium with a specific inhibitor, SEA0400. Action potentials were recorded from the myocardial layer of isolated guinea-pig pulmonary vein preparations,
Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka   +9 more
doaj   +1 more source

Progressive pulmonary vein stenosis in down syndrome infant: A rare cause of pulmonary hypertension

, 2018
Pulmonary veins stenosis in a Down Syndrome infant with normal connection pulmonary vein is rare and precise incidence of this disease is unknown. We report a case of progressive multiple pulmonary vein stenosis in a Down Syndrome infant with congenital ...
Sirisani, Joyce Darshinee Dom, Zahari, Norazah   +1 more
core  

Aspiration Is Associated with Poor Treatment Response in Pediatric Pulmonary Vein Stenosis

, 2021
Intraluminal pulmonary vein stenosis is a disease with significant morbidity and mortality, though recent progress has been made using multimodal therapy with antiproliferative agents.
Kathy J. Jenkins, Ryan Callahan, Maria Niccum, Kimberlee Gauvreau   +3 more
core   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Dissociated pulmonary vein potentials: expression of the cardiac autonomic nervous system following pulmonary vein isolation? [PDF]

, 2015
In the electrically nonisolated pulmonary veins, the cardiac autonomic system has been shown to play an important role in initiating pulmonary vein (PV) ectopy and triggering atrial fibrillation (AF).1–3 However, the effects of the cardiac autonomic ...
Peters, NS, Kanagaratnam, P, Kyriacou, A, Hayat, S, Qureshi, N, Lim, PB   +5 more
core   +1 more source