Results 81 to 90 of about 9,727 (224)

One-year follow-up of the effects of sildenafil on pulmonary arterial hypertension and veno-occlusive disease

Brazilian Journal of Medical and Biological Research, 2005
We hypothesized that chronic oral administration of the phosphodiesterase-5 inhibitor sildenafil could improve the exercise capacity and pulmonary hemodynamics in patients with pulmonary arterial hypertension (PAH) on the basis of previous short-term ...
A.C. Barreto, S.M. Franchi, C.R.P. Castro, A.A. Lopes   +3 more
doaj   +1 more source

Successful orthotopic liver transplantation in an adult patient with sickle cell disease and review of the literature [PDF]

, 2013
Sickle cell disease can lead to hepatic complications ranging from acute hepatic crises to chronic liver disease including intrahepatic cholestasis, and iron overload.
Blinder, Morey A., Chapman, William, Crippin, Jeffrey S., Field, Joshua J., Geng, B., Korenblat, Kevin, Lisker-Melman, Mauricio, Shenoy, Shalini   +7 more
core   +2 more sources

Immune‐related toxicity profile after haematopoietic stem cell transplantation in patients with B‐ALL given combination immunotherapy with rituximab, inotuzumab and blinatumomab

British Journal of Haematology, EarlyView.
Olayinka Okeleji, David McCall, Branko Cuglievan, Amber Gibson, Demetrios Petropoulos, Priti Tewari, Jeremy Connors, Irtiza N. Sheikh   +7 more
wiley   +1 more source

Recent Utilization of Pediatric Extrapolation and Modeling and Simulation Approaches in Pediatric Drug Development in Japan

The Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1889-1899, December 2025.
Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima, Akihide Tsujimoto, Masako Saito, Jun Takeda, Makiko Natori, Satoshi Shoji   +5 more
wiley   +1 more source

Clinical predictors of fetal and maternal outcome in Chinese patients with systemic lupus erythematosus [PDF]

, 2004
published_or_final_versio
Chan, TM, Lao, TH, Lau, CS, Leung, PY, Lo, Y, Mok, MY, Wong, WS   +6 more
core   +3 more sources

Malignant Rhabdoid Tumors of the Liver Are Associated With Inferior Outcomes Compared to Other Extracranial Rhabdoid Tumors

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Extracranial malignant rhabdoid tumors (eMRT) are rare, highly aggressive pediatric neoplasms. While the liver is a relatively common anatomic site of presentation, the clinical course of patients with hepatic eMRT (eMRT‐L) is not well described.
Sebastian Bühner, Katharina Gastberger, Stefanie Tüchert‐Knoll, Victoria E. Fincke, Pascal D. Johann, Patrick Melchior, Margarita Teleshova, Denis Kachanov, Alexey Shcherbakov, Irene Schmid, Kleoniki Roka, Reiner Siebert, Christian Vokuhl, Joachim Gerss, Jörg Fuchs, Rhoikos Furtwängler, Michael C. Frühwald   +16 more
wiley   +1 more source

Isolated pulmonary veno-occlusive disease and pulmonary arterial thrombosis in systemic sclerosis – a lethal combination

International Medical Case Reports Journal, 2010
Arun JeevaganGeneral Medicine, Ipswich NHS Hospital, UKBackground: Isolated pulmonary hypertension secondary to systemic sclerosis is not uncommon. Our patient with systemic sclerosis presented with a very aggressive form of pulmonary hypertension due to
Arun Jeevagan
doaj  

Connective tissue disease-associated pulmonary arterial hypertension. [PDF]

, 2015
Although rare in its idiopathic form, pulmonary arterial hypertension (PAH) is not uncommon in association with various associated medical conditions, most notably connective tissue disease (CTD).
Condliffe, R., Howard, L.S.
core   +2 more sources

Basiliximab in the Prophylaxis of aGVHD for Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: A Prospective, Multicenter, Open‐Label, Randomized Controlled Study

American Journal of Hematology, Volume 101, Issue 3, Page 628-632, March 2026.
Zhenbin Wei, Rongrong Liu, Lingling Shi, Qiaochuan Li, Lianjin Liu, Baoshi Zheng, Chunjie Qin, Hong Chen, Guyun Wang, Meiqing Wu, Gaohui Yang, Ruolin Li, Zhaoping Gan, Qi Zhou, Jing Fan, Xuemei Zhou, Yinghua Chen, Zhiyu Zeng, Zhongming Zhang, Yongrong Lai   +19 more
wiley   +1 more source

Kidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study

European Journal of Heart Failure, Volume 27, Issue 11, Page 2397-2409, November 2025.
Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer, Caroline Kellner, Benedikt N. Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak‐Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Sven Möbius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, P. Christian Schulze, Robert H.G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B. Winzer, Dirk Westermann, Benedikt Schrage   +41 more
wiley   +1 more source