Results 31 to 40 of about 7,830 (266)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Case Studies in Thermal EngineeringThis study explored the impact of pulsation on the hydro-thermal behavior of an interrupted microchannel heat sink. A homogeneous blend of Al2O3-water was employed as the coolant.
Saheed Adewale Adio +4 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Heat transfer in a pulsating flow in a converging channel
MATEC Web of Conferences, 2017 Experimental research of convective heat transfer in a plane converging channel has been conducted. Distributions of heat transfer coefficient on the channel wall in steady and pulsating air flow have been obtained.
Davletshin Irek +2 more
doaj +1 more source
The assessment bioenergy of cardiac contraction in the conditions of mechanical support circulation
Вестник трансплантологии и искусственных органов, 2019 Aim: to develop a new modified index for the assessment of bioenergy heart in conditions of heart failure. To assess the energy of the heart when using systems to bypass the left ventricle of the heart using non-pulsed flow pumps.
G. P. Itkin +3 more
doaj +1 more source
The Theory of Pulsating Flow in Conical Nozzles [PDF]
Journal of Applied Mechanics, 1963 A knowledge of the dynamic characteristics of nozzles and orifices is important in many control and stability analyses of engineering devices. It is usual to assume that the instantaneous flowrate, for a given set of inlet conditions and outlet pressure, is the same as the nontransient value for the same operating conditions.
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
EnergiesThis experimental study investigates the aerothermodynamic performance of a turbocharger turbine under steady and pulsating flow conditions across various turbine inlet temperatures (TITs) and pulsation frequencies. A power-based approach was implemented
Sina Kazemi Bakhshmand, Clemens Biet
doaj +1 more source