Results 51 to 60 of about 44,941 (309)

Intermittent accreting millisecond pulsars: light houses with broken lamps? [PDF]

, 2008
Intermittent accreting millisecond X-ray pulsars are an exciting new type of sources. Their pulsations appear and disappear either on timescales of hundreds of seconds or on timescales of days. The study of these sources add new observational constraints
Alessandro Patruno, D. Altamirano, Diego Altamirano, Manuel Linares, Nanda Rea, Nathalie Degenaar, P. Casella, Paolo Soleri, Piergiorgio Casella, Rudy Wijnands   +9 more
core   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Study of High-Frequency Pulsating Flow Control Valves

Applied Sciences
Pulsating flow signals are widely used in the fields of dynamic calibration of flow meters and reliability testing of fluid transmission pipelines.
Dongdong Zhang, Yunchen Wu, Kuankuan Zhu, Ruiyi Shi, Jian Ruan, Chuan Ding   +5 more
doaj   +1 more source

Sinusoidal shaped hollow fibers for enhanced mass transfer

, 2017
Inducing secondary flows and vortices is known to enhance mass transport. They can be imposed by structured flow channels for instance. In particular, these vortices reduce fouling and concentration polarization.
Breisig, Hans, Luelf, Tobias, Tepper, Maik, Wessling, Matthias   +3 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Effect of flow pulsation on heat transfer performance of biomimetic bark microchannel heat sink

Case Studies in Thermal Engineering
Pumping coolant or using pulse flow through microchannels with novel structures on microelectronic devices is suitable for high heat flux dissipation and sensor development. This study proposes a novel microchannel designed as a series of biomimetic bark
Robera Daba, Shanglong Xu, Weijie Wang, Yi Huang, Xinkai Luo, Kuang Fang   +5 more
doaj   +1 more source

Heat Transfer in Pulsating Flow [PDF]

Nature, 1954
WHEN pulsations are imposed on a flowing fluid, it may normally be expected that heat transfer to or from it would be changed because the pulsations would alter the thickness of the boundary layer and hence the thermal resistance. In the laminar region, this view is also supported by the fact shown by Richardson1 that the velocity profile for pulsating
H. A. HAVEMANN, N. N. NARAYAN RAO
openaire   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Tales of endings and beginnings : cycles of violence as a Leitmotif in the narrative structure of the Bhadrakāḷīmāhātmya [PDF]

, 2020
The asura’s demise at the hands of the goddess is a theme frequently revisited in Hindu myth. It is the chronicle of a death foretold. The Bhadrakāḷīmāhātmya, a sixteenth century regional purāṇa from Kerala, narrates the tale of fierce goddess Bhadrakāḷī
van Brussel, Noortje
core   +2 more sources