Results 41 to 50 of about 23,845 (57)

Liposome-enabled bufalin and doxorubicin combination therapy for trastuzumab-resistant breast cancer with a focus on cancer stem cells

Breast cancer stem cells (BCSCs) play a key role in therapeutic resistance in breast cancer treatments and disease recurrence. This study aimed to develop a combination therapy loaded with pH-sensitive liposomes to kill both BCSCs and the okbulk cancer ...
Gao, Yu, Shelling, Andrew N, Porter, David, Nolan, Emma, Wu, Zimei, Leung, Euphemia   +5 more
core   +1 more source

Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing

, 2016
Yusuke Doi,1 Amr S Abu Lila,1–3 Haruna Matsumoto,1 Tomoko Okada,1 Taro Shimizu,1 Tatsuhiro Ishida1 1Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan; 2Department of ...
Doi Y, Matsumoto H, Shimizu T, Abu Lila AS, Ishida T, Okada T   +5 more
core  

Enhanced efficacy of sublingual immunotherapy by liposome-mediated delivery of allergen

, 2017
Have Aliu,1–3 Carola Rask,1 Jens Brimnes,1 Thomas Lars Andresen2,3 1Immunology Department, In vivo Biology Team, ALK Abelló A/S, Hørsholm, 2Department of Micro- and Nanotechnology, Technical University of Denmark, 3Center for ...
Rask C, Aliu H, Andresen TL, Brimnes J
core  

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The working of a pulsatory liposome

Journal of Theoretical Biology, 2008
Under positive osmotic stress, a greater lipid vesicle swells to a critical diameter, when suddenly a transbilayer pore appears and grows to a maximum radius, then decreases and finally disappears. An amount of liquid was leaked out through the pore and the vesicle returns to the initial state and can start another cycle.
Dumitru Popescu
exaly   +3 more sources

A mathematical investigation on the active substance pulsatory release from a solution-charged liposome

BioSystems, 2019
We adopt a model in which the time evolution of a solution-charged liposome with selective permeability is seen as a sequence of two-stage cycles. In the first stage the lipid vesicle with a certain input concentration of the active substance is swelling up in an osmotic process until it reaches a size that one pore is formed on its surface. The second
Liviu Gr. Ixaru, Dumitru Popescu
exaly   +3 more sources

Analytical Modeling of the Functioning of the Pulsatory Liposome

Romanian Journal of Physics
In this paper the analytical solutions of the differential equations are presented. These equations describe the pulsatory liposome dynamics. We consider a unilamellar liposome filled with an aqueous solution of osmotic solute inserted in a hypotonic aqueous medium. Due to the osmosis process the liposome has a cyclic evolution.
Dumitru Popescu
exaly   +2 more sources

AN ANALYTICAL APPROACH FOR THE PULSATORY LIPOSOME IN THE PORE RADIUS HYPOTHESIS

Revue roumaine de mathématiques pures et appliquées
One considers a unilamellar liposome filled with an aqueous solution of an osmotic solute. This liposome is introduced into an aqueous medium. Due to the osmosis process, the lipid vesicle swells up to a maximum size, when a transbilayer pore suddenly appears. Part of the internal solution leaks through this pore.
Dumitru Popescu
exaly   +2 more sources

Numerical Simulation of Lifetime for the Pulsatory Liposome

Macromolecular Symposia
ABSTRACT One considers a unilamellar liposome filled with an aqueous solution of an osmotic solute. This liposome is introduced into an aqueous medium. Due to the osmosis process, the lipid vesicle swells up to a maximum size, when a transbilayer pore suddenly appears. Part of the internal solution leaks through this pore.
Dumitru Popescu
exaly   +2 more sources

Pulsatory andesite lava flow at Bagana Volcano [PDF]

Geochemistry, Geophysics, Geosystems, 2012
Using a time series of TerraSAR-X spaceborne radar images we have measured the pulsatory motion of an andesite lava flow over a 14-month period at Bagana volcano, Papua New Guinea. Between October 2010 and December 2011, lava flowed continuously down the
Geoffrey Wadge
exaly   +2 more sources

Microactuation of Magnetic Nanofluid Enabled by a Pulsatory Rotating Magnetic Field

Actuators, 2023
Lucian Pislaru-Danescu, Chihaia Rares Andrei, Eros-Alexandru Patroi   +2 more
exaly