Results 71 to 80 of about 877,845 (325)

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont   +4 more
wiley   +1 more source

Arterial pulse wave pressure transducer [PDF]

open access: yes, 1974
An arterial pulse wave pressure transducer is introduced. The transducer is comprised of a fluid filled cavity having a flexible membrane disposed over the cavity and adapted to be placed on the skin over an artery.
Chen, W., Gorelick, D., Kim, C.
core   +1 more source

Fluid-structure interaction simulation of pulse propagation in arteries : numerical pitfalls and hemodynamic impact of a local stiffening [PDF]

open access: yes, 2014
When simulating the propagation of a pressure pulse in arteries, the discretization parameters (i.e. the time step size and the grid size) need to be chosen carefully in order to avoid a decrease in amplitude of the traveling wave due to numerical ...
Degroote, Joris   +4 more
core   +1 more source

Pulse Pressure and Cardiovascular Death

open access: yesJournal of the American College of Cardiology, 2016
We read with great interest the study of Selvaraj et al. [(1)][1], which provides robust evidence on the predictive role of pulse pressure (PP) for cardiovascular (CV) outcomes. Surprisingly, however, when the predictive ability of a 10 mm Hg increase in PP was assessed, a “protective ...
Charalambos Vlachopoulos   +2 more
openaire   +3 more sources

Treating lupus nephritis patients to lupus low disease activity reduces renal relapse and preserves long‐term kidney function

open access: yesArthritis Care &Research, Accepted Article.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung   +6 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

Peak expiratory flow rate and Pulse Pressure values during the Luteal and Menstruation Phases of the Menstrual Cycle

open access: yesJournal of Applied Sciences and Environmental Management, 2016
This study assessed the peak expiratory flow rate and pulse pressure during the luteal and menstruation phases of the menstrual cycle. The peak expiratory flow rate and pulse pressure were measured using the Wright’s Peak Flow Meter and Mercury ...
A Omorogiuwa, M Ojiemudia
doaj   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

open access: yesAdvanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran   +5 more
wiley   +1 more source

Development of pulse diagnostic devices in Korea

open access: yesIntegrative Medicine Research, 2013
In Korean medicine, pulse diagnosis is one of the important methods for determining the health status of a patient. For over 40 years, electromechanical pulse diagnostic devices have been developed to objectify and quantify pulse diagnoses. In this paper,
Hyunho Kim   +3 more
doaj   +1 more source

Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease. [PDF]

open access: yesPLoS ONE, 2014
A seeming paradox of sickle cell disease is that patients do not suffer from a high prevalence of systemic hypertension in spite of endothelial dysfunction, chronic inflammation and vasculopathy.
Enrico M Novelli   +7 more
doaj   +1 more source

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