Results 31 to 40 of about 7,411,293 (290)

Feasibility Study on Atrial Fibrillation Ablation with Pulsed Field Ablation and concomitant Occlusion of the Left Atrial Appendage. [PDF]

BACKGROUND AND AIMS Atrial fibrillation (AF) ablation and left atrial appendage occlusion (LAAO) are increasingly performed as individual procedures. Pulsed field ablation (PFA) has significantly reduced procedure duration and may be advantageous for ...
Kueffer, Thomas, Siontis, Georgios, Brugger, Nicolas, Beney, Jennifer, Galea, Roberto, Roten, Laurent, Räber, Lorenz, Reichlin, Tobias, Gräni, Christoph   +8 more
core   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

First worldwide use of pulsed‐field ablation for ventricular tachycardia ablation via a retrograde approach [PDF]

, 2023
Introduction: We present the first worldwide use of pulsed‐field ablation (PFA) for ventricular tachycardia (VT) ablation via a retrograde approach. Methods: The patient had previously failed conventional ablation of an intramural circuit underneath the ...

core   +3 more sources

Pulsed field ablation: Biophysical principles and practical considerations in atrial fibrillation treatment

Indian Pacing and Electrophysiology Journal
Pulsed field ablation (PFA) is an emerging nonthermal ablation modality for the treatment of atrial fibrillation. Unlike conventional thermal energy sources such as radiofrequency and cryoablation, PFA delivers high-voltage pulsed electric fields that ...
Shivaraj Patil, Suraj Kapa, Abhishek J. Deshmukh   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Numerical Modeling of Excimer Laser Curved Surface Ablation [PDF]

, 2013
Laser ablation has been widely used in the fabrication of miniature parts. The technique is also used in the fabrication of micro lens or micro-curved surfaces which find potential applications in various optical, bio- medical, electronics, MEMS ...
Marla, Deepak, Saxena, Ishan, Joshi, Suhas S., Garg, Vivek   +3 more
core  

Pulsed Field Ablation for the Interventional Treatment of Cardiac Arrhythmias

, 2022
International audiencePulsed field ablation is a recent addition to the techniques used to ablate pathological arrhythmic circuits. Despite its recent introduction in the clinical field, pulsed field ablation exploits the well-known phenomenon of ...
Caluori, Guido, Poignard, Clair, Collin, Annabelle, Jais, Pierre   +3 more
core   +1 more source

Impact of Left Atrial Posterior Wall Ablation During Pulsed-Field Ablation for Persistent Atrial Fibrillation. [PDF]

BACKGROUND Pulmonary vein isolation (PVI) alone is insufficient to treat many patients with persistent atrial fibrillation (PersAF). Adjunctive left atrial posterior wall (LAPW) ablation with thermal technologies has revealed lack of efficacy, perhaps
Metzner, Andreas, Wakili, Reza, Sommer, Philipp, Fueting, Anna, Deneke, Tom, Gunawardene, Melanie, Ouss, Alexandre, Funasako, Moritoshi, Rollin, Anne, Chaumont, Corentin, Turagam, Mohit K., Scherr, Daniel, Reddy, Vivek Y., Reinsch, Nico, Willems, Stephan, Bohnen, Jan-Eric, Boveda, Serge, Reddy, Vivek Y, Hansen , Jim, Mulder, Bart A.; id_orcid, Hansen, Jim, Reichlin, Tobias, Anic, Ante, Fink, Thomas, Roten, Laurent, Derval, Nicolas, Jais, Pierre, van der Voort, Pepijn, Heeger, Christian Hendrik, Manninger, Martin, Sultan, Arian, Kueffer, Thomas, Maury, Philippe, Turagam, Mohit K, Vijgen, Johan, Peichl, Petr, Mulder, Bart A., Bohnen, Jan Eric, Mulder, Bart A, Neven , Kars, Nentwich, Karin, Kautzner, Josef, Willems , Stephan, Anselme, Frederic, Neven, Kars, Chun, Julian, Neuzil, Petr, Petru, Jan, Blaauw, Yuri, Jurisic, Zrinka, Lehrmann, Heiko, Arentz, Thomas, Schmidt, Boris, Koopman, Pieter, Steven, Daniel, Adelino, Raquel, Lemoine, Marc D., Tilz, Roland, Heeger, Christian-Hendrik, Füting, Anna, Lemoine, Marc D, Ruwald, Martin   +61 more
core   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Pulsed-Field Ablation Using a Novel Ablation-Mapping Integrated System for Pulmonary Vein Isolation—A Preliminary Animal Study

Journal of Cardiovascular Development and Disease, 2022
Objective: The purpose of this study is to evaluate the preliminary safety and effect of a pulsed electric field (PEF) ablation system. Methods: The pulmonary veins (PVs) and superior vena cava (SVC) were isolated with the pulsed field ablation (PFA ...
Zhihong Zhao, Yonggang Chen, Bin Wu, Gaodong Qiu, Liangjie Hong, Xinhua Chen, Xingwei Zhang   +6 more
doaj   +1 more source