Results 151 to 160 of about 3,654 (184)

Multifaceted Neuroprotective Role of Punicalagin: A Review

Neurochemical Research, 2023
Millions of people worldwide are currently afflicted with neurologic conditions like a seizure, depression, stress, Alzheimer's disease, Parkinson's disease, and Huntington's disease. However, the precise etiopathology of these diseases is still unknown. Substantial studies are being conducted to discover more treatments against these disorders because
Nazia, Siddiqui, Alimuddin, Saifi, Anurag, Chaudhary, Prabhash Nath, Tripathi, Ankit, Chaudhary, Alok, Sharma   +5 more
openaire   +2 more sources

Punicalagin inhibits neuroinflammation in LPS‐activated rat primary microglia

Molecular Nutrition and Food Research, 2014
Scope In this study, the effects of punicalagin on neuroinflammation in LPS-activated microglia were investigated. Methods and results The ability of punicalagin to reduce the production of TNF-α, IL-6 and prostaglandin E2 was measured in culture ...
Ravikanth Velagapudi, Olumayokun A Olajide, Bernd L Fiebich   +2 more
exaly   +2 more sources

One-Step Purification of Punicalagin by Preparative HPLC and Stability Study on Punicalagin

Separation Science and Technology, 2010
A novel, rapid, and high efficiency method to purify natural punicalagin by preparative HPLC is described. The optimum purification condition for punicalagin purification was 14% methanol in 0.1% trifluoroacetic acid solution as the mobile phase. The flow rate was 12 ml/min.
Ke Ding
exaly   +2 more sources

Punicalagin alleviates hepatotoxicity in rats challenged with cyclophosphamide

Environmental Toxicology and Pharmacology, 2016
This study investigated the possible hepatoprotection of punicalagin in rats received cyclophosphamide (20mg/kg/day, i.p., for 7 days). Punicalagin given at two doses, 15 and 30mg/kg/day, p.o., for 7 days, starting the same day of cyclophosphamide administration.
Hatem O Qutub, Amr Fouad
exaly   +3 more sources

Punicalagin is a neuraminidase inhibitor of influenza viruses

Journal of Medical Virology, 2020
AbstractInfluenza A virus (IAV) causes great morbidity and mortality worldwide every year. However, there are only a limited number of drugs clinically available against IAV infection. Further, emergence of drug‐resistant strains can render those drugs ineffective. Thus there is an unmet medical need to develop new anti‐influenza agents. In this study,
Ping, Li, Ruikun, Du, Zinuo, Chen, Yanyan, Wang, Peng, Zhan, Xinyong, Liu, Dongwei, Kang, Zhaoyu, Chen, Xiujuan, Zhao, Lin, Wang, Lijun, Rong, Qinghua, Cui   +11 more
openaire   +2 more sources

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway

Nutrients, 2020
Diabetic nephropathy is a diabetic complication caused by chronic inflammation. As the primary polyphenol in pomegranate, punicalagin is believed to have significant anti-inflammatory properties.
Hong Qin, Lina Yang, Jihua Chen
exaly   +2 more sources

Punicalagin Prevents Inflammation in LPS- Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway

Nutrients, 2019
Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects, including inhibiting production of pro-inflammatory cytokines in macrophages.
Guofeng Ren, Lina Yang, Jihua Chen
exaly   +2 more sources

Exploring Punicalagin Potential Against Cancers: A Comprehensive Review

Food Science and Nutrition
ABSTRACTPunicalagin, being a bioactive polyphenol, has gained significant interest owing to its potential anticancer effects. Researchers are studying punicalagin to determine its ability to inhibit cancer cell proliferation. This paper focuses on highlighting the therapeutic potential of punicalagin against tumors and cancers.
Tadesse Fenta
exaly   +3 more sources

ChemInform Abstract: On the Structure of Punicalagin and Punicalin.

Chemischer Informationsdienst, 1986
AbstractThe tanning agents punicalagin (I) and punicalin (II) both form an equilibrium mixture of α,β‐anomers.
G. SCHILLING, H. SCHICK
openaire   +1 more source

Gastroprotective activity of punicalagin and Lafoensia pacari in mice

Revista Brasileira de Farmacognosia, 2020
Lafoensia pacari A. St.-Hil., Lythraceae, is used in Brazilian folk medicine to treat ulcer and gastritis; thus, it is important to conduct research so as to better understand its medicinal properties. The aim of this study was to assess the antisecretory and antiulcerogenic activities of lyophilized aqueous fraction and punicalagin isolated from ...
Beatriz A. Chaibub, José L. R. Martins, José R. de Paula, Suzana da C. Santos, Elson A. Costa, Maria Teresa F. Bara   +5 more
openaire   +1 more source