Results 81 to 90 of about 2,748 (167)

Pomegranate Peel Extract Microemulsions for Skin Delivery: Insights into Drug Release, Skin Permeation and UV Protection

Cosmetics
Pomegranate peel, an abundant agro-industrial by-product, represents a sustainable source of bioactive polyphenols, particularly punicalagin, which has been associated with antioxidant and photoprotective potential.
Nataša Bubić Pajić, Teodora Trninić, Darija Knežević Ratković, Vesna Antunović, Katarina Šavikin, Jelena Živković, Ranko Škrbić   +6 more
doaj   +1 more source

Computational investigations of potential inhibitors of monkeypox virus envelope protein E8 through molecular docking and molecular dynamics simulations

Scientific Reports
The World Health Organization (WHO) has declared the monkeypox outbreak a public health emergency, as there is no specific therapeutics for monkeypox virus (MPXV) disease. This study focused on docking various commercial drugs and plant-derived compounds
Rohit Das, Anil Bhattarai, Rohit Karn, Buddhiman Tamang   +3 more
doaj   +1 more source

The Role of Punicalagin in Slowing Down the Decaying of Neurons

Malaysian Journal of Medical and Biological Research, 2017
Punicalagin is an active compound found in the Pomegranate rind. The hallmark of the compound is its antioxidant properties which is more than most other sources such as Red wine. The poly-phenol donates hydrogen to free radicals like peroxynitrites and prevents it from oxidizing and destroying microglial cells in the brain.
openaire   +1 more source

Anti‐inflammatory effects of punicalagin on LPS‐activated microglia

The FASEB Journal, 2019
Pomegranate ( Punica granatum L.) is a popular fruit originated in the Middle East and has been widely planted around the world. It contains various phytochemicals such as polyphenolic compounds and has a wide range of biological activities, including anti‐inflammatory, anti‐tumor ...
Yueh‐Shan Lee, Yi‐Xin Lai, Chia‐Yang Li   +2 more
openaire   +1 more source

Cognition enhancement of Punicalagin following intracerebroventricular injection of Aβ (25-35) model of mice: Cognition enhancement of Punicalagin

International Journal of Biomedical and Advance Research, 2018
The hallmark in the pathology of Alzheimer disease is the deposition of amyloid plaques throughout the brain which lead to the deterioration of neuronal function and eventually they die. This damage spreads to hippocampus, region responsible for forming memories. This will ultimately lead to impairment in cognition.
Ittiyavirah, Sibi P, Raju, Rakhi
openaire   +1 more source

Analysis of Osteosarcoma Cell Lines and Patient Tissue Using a 3D In Vivo Tumor Model—Possible Effects of Punicalagin

Organoids
Osteosarcomas are the most common primary malignant bone tumors and mostly affect children, adolescents, and young adults. Despite current treatment options such as surgery and polychemotherapy, the survival of patients with metastatic disease remains ...
Anna Rebecca Dorn, Sara Neff, Sophia Hupp, Melissa Engelhardt, Eric Pion, Ulrich Lenze, Carolin Knebel, Anna Duprée, Simone Schewe, Markus Weber, Christian Wulbrand, Axel Hillmann, Florian Weber, Phillip Clarke, Philipp Kainz, Thiha Aung, Silke Haerteis   +16 more
doaj   +1 more source

Anticancer effects of Punicalagin

Haydarpasa Numune Training and Research Hospital Medical Journal, 2021
openaire   +1 more source

The polyphenolic compound punicalagin protects skin fibroblasts from UVA radiation oxidative damage

Current Research in Pharmacology and Drug Discovery
Polyphenols are a class of natural compounds that act as antioxidants, neutralising harmful free radicals that would damage cells and increase the risk of diseases such as cancer, diabetes and heart disease.
Giada Bianchetti, Patrizia Bottoni, Giuseppe Tringali, Giuseppe Maulucci, Elisabetta Tabolacci, Maria Elisabetta Clementi   +5 more
doaj   +1 more source

Study on the Effects of Tannase on the De Astringency of Pomegranate Juice

Foods
Reducing the punicalagin content is an effective strategy for eliminating the astringency of pomegranate juice. In this study, pomegranate juice was used as the raw material, and tannase was applied to convert punicalagin into ellagic acid and gallic ...
Guida Zhu, Longwen Wang, Han Wang, Zihan Chen, Xue Li, Yi Ji, Jing Yu, Ping Song   +7 more
doaj   +1 more source

Helicase A determines the transcription program of T_H17 lineage differentiation and autoimmunity. [PDF]

Sci Adv
Su Y, Jiao A, Zhang X, Xu Y, Ping H, Zhu K, Wang Q, Yuan N, Gao Y, Ju B, Ding R, Wang N, He L, Lei L, Zhao Y, Zhang M, Zhang B.   +16 more
europepmc   +1 more source