Results 61 to 70 of about 2,740 (167)

Potential role of punicalagin against oxidative stress induced testicular damage

Asian Journal of Andrology, 2016
Punicalagin is isolated from pomegranate and widely used for the treatment of different diseases in Chinese traditional medicine. This study aimed to evaluate the effect of Punicalagin (purity ≥98%) on oxidative stress induced testicular damage and its ...
Faiza Rao, Hui Tian, Wenqing Li, Helong Hung, Fei Sun   +4 more
doaj   +1 more source

Polyphenolic Components and Phytochemicals Deployed as Nutraceuticals and Pharmafoods

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This review (2010–2025) highlights the therapeutic potential of dietary polyphenols against cancer, diabetes, cardiovascular, neurological, and inflammatory diseases. It summarizes molecular mechanisms, clinical evidence, nanoparticle‐based delivery, bioavailability, safety, toxicity, and future prospects supporting polyphenols as promising therapeutic
Subhash Chandra, Md. Sakib Al Hasan, Md. A. K. Azad, Atasi Goswami   +3 more
wiley   +1 more source

Comparative analysis of the phenolic contents and antioxidant activities of different parts of two pomegranate (Punica granatum L.) Cultivars: ‘Tunisia’ and ‘Qingpi’

Frontiers in Plant Science, 2023
Pomegranate (Punica granatum L.), with its abundant phenolic substances and strong antioxidant activity, holds significant research and utilization potential across various organs.
Huifen Zhang, Miao Wang, Guoqiang Yu, Jing Pu, Kun Tian, Xiaofu Tang, Ying Du, Hongxia Wu, Jiong Hu, Xian Luo, Lijin Lin, Qunxian Deng   +11 more
doaj   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, Volume 40, Issue 7, Page 4588-4610, July 2026.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source

Synergistic Effects of Carrier Composition and Spray‐Drying Conditions on the Microencapsulation of Pomegranate Peel Extract

Journal of Food Process Engineering, Volume 49, Issue 7, July 2026.
Spray drying conditions and carrier composition significantly affected the retention of bioactive compounds in pomegranate peel extract powders. The synergistic combination of maltodextrin and gum arabic enhanced process yield, ellagic acid retention, total phenolic content, and antioxidant activity under optimized drying conditions.
Nida Pınarbaşı, Aslı Arslan Kulcan, Ferhan Balcı‐Torun, Ayhan Topuz   +3 more
wiley   +1 more source

Punicalagin Induces Serum Low‐Density Lipoprotein Influx to Macrophages [PDF]

Oxidative Medicine and Cellular Longevity, 2016
High levels of circulating low‐density lipoprotein (LDL) are a primary initiating event in the development of atherosclerosis. Recently, the antiatherogenic effect of polyphenols has been shown to be exerted via a mechanism unrelated to their antioxidant capacity and to stem from their interaction with specific intracellular or plasma proteins. In this
Dana Atrahimovich, Soliman Khatib, Shifra Sela, Jacob Vaya, Abraham O. Samson   +4 more
openaire   +2 more sources

Advances in Eco‐Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions

Analytical Science Advances, Volume 7, Issue 1, June 2026.
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya, Desta Berhe Sbhatu, Gebreselema Gebreyohannes   +2 more
wiley   +1 more source

Analysis of Punicalin and Punicalagin Interaction with PDIA3 and PDIA1

International Journal of Molecular Sciences
PDIA3 is a pleiotropic protein primarily located in the endoplasmic reticulum where it is involved in protein folding, catalyzing the formation, breakage, and rearrangement of disulfide bonds. PDIA3 is implicated in numerous pathologies such as cancer, inflammation, and neurodegeneration.
Meschiari, Giorgia, Minacori, Marco, Fiorini, Sara, Tedesco, Mariassunta, Eufemi, Margherita, Altieri, Fabio   +5 more
openaire   +3 more sources

Anticancer effects of punicalagin and 5-fluorouracil on laryngeal squamous cell carcinoma: an in vitro study

Italian Journal of Medicine
The purpose of this study was to assess the apoptotic effects of punicalagin alone and in combination with 5-fluorouracil (5-FU) on laryngeal squamous cell carcinoma (Hep-2) cell line.
Amany M. Taha, Eman Abd-Elshafy, Asmaa M. Khalifa, Najla Dar-Odeh, Shadia Elsayed, Daniah S. Alharkan, Aishah Alhodhodi, Ahmed Mohammed Sapri, Yassmeen SalahEldin Ragheb, Gihan A. Balbola   +9 more
doaj   +1 more source

Antibacterial and antioxidant effects of Punicalagin extracts from Punica granatum peels [PDF]

Caspian Journal of Environmental Sciences
The growing recognition of the health-promoting potential of compounds derived from natural sources, particularly those exhibiting antimicrobial and antioxidant activities, has resulted in a surge of research publications dedicated to exploring the ...
Saidakhon T. Islamova, Moxira A. Nazarova, Aktam U. Burkhanov, Fayzulla Khamraev, B.U. Isagova, Sherali Xamdamov, Nodira Sh. Nazarova, Fazliddin F. Zubaydov, Dilafruz S. Khursandova, Oyatillo U. Badriddinov   +9 more
doaj   +1 more source