Results 161 to 170 of about 3,672 (187)

Multifaceted Neuroprotective Role of Punicalagin: A Review

Neurochemical Research, 2023
Millions of people worldwide are currently afflicted with neurologic conditions like a seizure, depression, stress, Alzheimer's disease, Parkinson's disease, and Huntington's disease. However, the precise etiopathology of these diseases is still unknown. Substantial studies are being conducted to discover more treatments against these disorders because
Nazia, Siddiqui, Alimuddin, Saifi, Anurag, Chaudhary, Prabhash Nath, Tripathi, Ankit, Chaudhary, Alok, Sharma   +5 more
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Punicalagin alleviates hepatotoxicity in rats challenged with cyclophosphamide

Environmental Toxicology and Pharmacology, 2016
This study investigated the possible hepatoprotection of punicalagin in rats received cyclophosphamide (20mg/kg/day, i.p., for 7 days). Punicalagin given at two doses, 15 and 30mg/kg/day, p.o., for 7 days, starting the same day of cyclophosphamide administration.
Hatem Othman Qutub, Amr A. Fouad
exaly   +3 more sources

Punicalagin is a neuraminidase inhibitor of influenza viruses

Journal of Medical Virology, 2020
AbstractInfluenza A virus (IAV) causes great morbidity and mortality worldwide every year. However, there are only a limited number of drugs clinically available against IAV infection. Further, emergence of drug‐resistant strains can render those drugs ineffective. Thus there is an unmet medical need to develop new anti‐influenza agents. In this study,
Ping, Li, Ruikun, Du, Zinuo, Chen, Yanyan, Wang, Peng, Zhan, Xinyong, Liu, Dongwei, Kang, Zhaoyu, Chen, Xiujuan, Zhao, Lin, Wang, Lijun, Rong, Qinghua, Cui   +11 more
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Punicalagin Prevents Inflammation in LPS- Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway

Nutrients, 2019
Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects, including inhibiting production of pro-inflammatory cytokines in macrophages.
Guofeng Ren, Lina Yang, Jihua Chen
exaly   +2 more sources

ChemInform Abstract: On the Structure of Punicalagin and Punicalin.

Chemischer Informationsdienst, 1986
AbstractThe tanning agents punicalagin (I) and punicalin (II) both form an equilibrium mixture of α,β‐anomers.
G. SCHILLING, H. SCHICK
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Gastroprotective activity of punicalagin and Lafoensia pacari in mice

Revista Brasileira de Farmacognosia, 2020
Lafoensia pacari A. St.-Hil., Lythraceae, is used in Brazilian folk medicine to treat ulcer and gastritis; thus, it is important to conduct research so as to better understand its medicinal properties. The aim of this study was to assess the antisecretory and antiulcerogenic activities of lyophilized aqueous fraction and punicalagin isolated from ...
Beatriz A. Chaibub, José L. R. Martins, José R. de Paula, Suzana da C. Santos, Elson A. Costa, Maria Teresa F. Bara   +5 more
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Effects of Punicalagin and Punicalin on Carrageenan-Induced Inflammation in Rats

The American Journal of Chinese Medicine, 1999
Punicalagin and punicalin were isolated from the leaves of Terminalia catappa L. In this study, we evaluated the anti-inflammatory activity of punicalagin and punicalin carrageenan-induced hind paw edema in rats. After evaluation of the anti-inflammatory effects, the edema rates were increased by carrageenan administration and reduced by drug ...
C C, Lin, Y F, Hsu, T C, Lin
openaire   +2 more sources

Cardioprotective potential of punicalagin: an evidence-based review

Journal of Asian Natural Products Research
This evidence-based review highlights the cardioprotective potential of punicalagin, a major polyphenolic ellagitannin from Punica granatum L., focusing on its pharmacological mechanisms in cardiovascular disease (CVD) pathogenesis. Preclinical studies demonstrate that punicalagin reduces oxidative stress via Nrf2/HO-1 and AMPK pathways, suppresses ...
Gurjeet, Kaur, Rupali, Chauhan, Gauri, Kashyap, Jayant, Goyal, Neeraj, Mittal, Parveen, Kumar, Sushma, Devi   +6 more
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Zur Struktur des Punicalagins und Punicalins

Liebigs Annalen der Chemie, 1985
AbstractDie Gerbstoffe Punicalagin (1) und Punicalin (2) bilden in Lösung ein α,β‐Anomerengemisch. Die spektroskopischen Daten zeigen, daß diese Moleküle als natürliche Ansa‐Verbindungen angesehen werden können. Unter den Bedingungen der Glycosylierung weicht das System bei 2 in Richtung größerer Beweglichkeit des Makrocyclus aus: Entweder durch ...
Gerhard Schilling, Hartmut Schick
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Immune-suppressive activity of punicalagin via inhibition of NFAT activation

Biochemical and Biophysical Research Communications, 2008
Since T cell activation is central to the development of autoimmune diseases, we screened a natural product library comprising 1400 samples of medicinal herbal extracts, to identify compounds that suppress T cell activity. Punicalagin (PCG) isolated from the fruit of Punica granatum was identified as a potent immune suppressant, based on its inhibitory
Sang-Ik, Lee, Byoung-Soo, Kim, Kyoung-Shin, Kim, Samkeun, Lee, Kwang-Soo, Shin, Jong-Soon, Lim   +5 more
openaire   +2 more sources