Results 51 to 60 of about 2,761 (165)
Experimental Physiology, EarlyView.Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
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Punicalagin Induces Serum Low‐Density Lipoprotein Influx to Macrophages [PDF]
Oxidative Medicine and Cellular Longevity, 2016 High levels of circulating low‐density lipoprotein (LDL) are a primary initiating event in the development of atherosclerosis. Recently, the antiatherogenic effect of polyphenols has been shown to be exerted via a mechanism unrelated to their antioxidant capacity and to stem from their interaction with specific intracellular or plasma proteins. In this
Dana Atrahimovich +4 more
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Punicalagin and Punicalin Suppress the Adipocyte Differentiation through the Transcription Factors
Acta Endocrinologica (Bucharest), 2021 Pomegranate is a rich source of many polyphenolic compounds including ellagitannins (punicalagin, punicalin and others).The effects of punicalagin and punicalin on adipogenesis were investigated in this study.To examine the effect of punicalagin and punicalin on adipocyte differentiation, various concentrations of punicalagin and punicalin (2-10 µM ...
Yalın, A E +4 more
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Food Science &Nutrition, Volume 14, Issue 9, September 2026.Raw materials: Natural wall materials. Extraction: Pomegranate in ethanol (80%), 1:10 ratio, 2 days, 4°C, Phenolic extract preparation. Encapsulation: Two‐Stage Lyophilization (Orange Peel), Stage 1: Mix extract + orange peel (4:1); −40°C, 24 h, Stage 2: Re‐mix (3:1); −40°C, 24 h, 7:1, Single‐stage lyophilization (Commercial Pectin), Mix extract ...
Marwa Ezz El‐Din Ibrahim +1 more
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eFood, Volume 7, Issue 4, August 2026.Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang +6 more
wiley +1 more source
Anthelmintic Activity of Punicalagin from nogeissus Leiocarpus [PDF]
Universal Journal of Plant Science, 2015 Leaves of Anogeissus leiocarpus Guill. & Perr. have been traditionally used as an African botanical treatment for parasitic worm infections in both humans and livestock. This current study documents the presence of punicalagin isomers (α & β) and its galloyl ester, 1-O-galloyl-punicalagin as major components in the leaf extract of A.
Carrie Waterman +6 more
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Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
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Antioxidant Activity of Pomegranate Juice and Punicalagin
Natural Science, 2016 Plant polyphenols are reported to have bioactive properties, which may be used for protection against diseases. Therefore, the aim of this research was to investigate the antioxidant activities of a pomegranate tannin polyphenol compound, punicalagin and pomegranate juice. The presence of punicalagin in pomegranate husk (US) and pomegranate juice (US &
Akram Aloqbi +5 more
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Punicalagin Restricts Growth, Promotes Apoptosis, and Reduces Invasion in Human Gastric Cancer Cells
Dose-ResponseThis research investigated the anticancer properties of punicalagin, a prominent bioactive polyphenol extracted from Punica granatum L, in human gastric cancer cell lines. Normal and gastric cancer cells were exposed to different doses of punicalagin for
Ding-Ping Sun +6 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.The graphical abstract illustrates the action mechanisms through which PPE alleviates HUA by inhibiting XOD activity, and by suppressing the PI3K‐AKT signaling pathway to downregulate the expression of the urate reabsorption transporters URAT1 and GLUT9, thereby promoting renal UA excretion and attenuating renal injury.
Zeyu Yin +6 more
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