Results 51 to 60 of about 865,036 (193)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Experimental investigation of indirect heat transfer through a novel designed lab-scale setup using functionalized MWCNTs nanofluids (MWCNTs-COOH/water and MWCNTs- OH/water)

Case Studies in Thermal Engineering, 2023
This study aims to investigate the influence of functionalized multi-walled carbon nanotubes (MWCNTs-COOH and MWCNTs-OH) on the performance of a novel indirect laboratory heater redesigned with a helical tube.
Nazanin Karimi Bakhtiyar, Sama Esmaeili, Reza Javadpour, Saeed Zeinali Heris   +3 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Chitosan/Poly(Amide-Imide) Blend Films: Studies on Thermal and Mechanical Stability, Morphology and Biodegradability [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
A diacid monomer was synthesized by the condensation of L-tryptophan amino acid and pyromellitic dianhydride (PMDA). The diacid was utilized for the synthesis of three types of poly(amide-imide)s (PAIs) using three different kinds of diamines.
Mahdiyeh Ghasemi, Elaheh Kowsari, Ali Amoozadeh   +2 more
doaj  

Hyperbranched polysiloxane functionalized graphene oxide for dicyclopentadiene bisphenol dicyanate ester nanocomposites with high performance

eXPRESS Polymer Letters, 2014
We report an efficient and novel method to functionalize graphene oxide (GO) with hyperbranched polysiloxane and successfully compound them with dicyclopentadiene bisphenol dicyanate ester (DCPDCE) to prepare nanocomposites.
H. X. Yan, M. M. Zhang, C. Gong, T. T. Li   +3 more
doaj   +1 more source

Real-time quantitative analysis of volatile products generated during solid-state polypropylene thermal oxidation [PDF]

, 2013
Analysis of volatile organic compounds (VOCs) during PP thermal oxidation under three oxygen partial pressures (0%, 21% and 100% of atmospheric pressure) at 140 C was performed by proton transfer reaction coupled with Fourier transform ion cyclotron ...
COLIN, Xavier, DESNOUX, Eric, FRANCOIS-HEUDE, Alexandre, HENINGER, Michel, LEPROVOST, Julien, MESTDAGH, Helene, RICHAUD, Emmanuel   +6 more
core   +4 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Investigation of the 2nd generation of intact stability criteria in parametric rolling and pure loss of stability [PDF]

, 2015
The International Maritime Organisation is developing the second generation intact stability criteria which include parametric rolling, pure loss of stability and the other three failure modes. This paper will focus on the application of the draft parametric rolling and pure loss of stability criteria on the well-known post-Panamax C11 class ...
Liu, Haipeng, Turan, Osman, Boulougouris, Evangelos   +2 more
openaire  

Design of surface-active artificial enzyme particles to stabilize Pickering emulsions for high-performance biphasic biocatalysis [PDF]

, 2015
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Surface-active artificial enzymes (SAEs) are designed and constructed by a general and novel strategy.
Baciocchi, Binks, Bonomi, Chen, Chen, Crossley, Dewey, Diez-Castellnou, Gao, Jiang, Kapil, Kosif, Köhler, Li, Li, Lin, Liu, Liu, Mondloch, Nanda, Natalio, Neverov, Pengo, Pera-Titus, Silverman, Smith, Song, Sun, Tonga, Vernekar, Wang, Wang, Wang, Wiese, Wu, Yang, Zapata, Zaramella, Zhang, Zhou   +39 more
core   +1 more source