Results 51 to 60 of about 166,378,893 (241)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Chemical Stability and Dissolution of Paracetamol Tablets Formulated by Direct Compression and Granulation Process

Acta Chimica Slovenica
The chemical stability of active substances affects the safety and efficacy of the drug products. The aim of this study was to investigate the stability and dissolution of paracetamol tablets produced by wet granulation (GS, GP) and direct compression ...
Nemanja B. Todorović, Darija B. Sazdanić, Bojana G. Mamužić, Mladena N. Lalić-Popović, Milica T. Atanacković Krstonošić, Mira P. Mikulić   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Preparation of Composite Insulating Paper With Decreased Permittivity, Good Mechanical and Thermal Properties by Kevlar/Nano Cellulose Fibrils/Softwood Pulp Hybrid

IEEE Access, 2019
Kevlar pulp treated with low-temperature plasma and nano cellulose fibrils (NCFs) have been introduced as reinforcements in the preparation for composite insulating paper with low relative permittivity, dielectric loss, good mechanical properties, and ...
Yang Mo, Lijun Yang, Tiantian Zou, Wei Hou, Ruijin Liao   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Unlocking the Potential of Li–Ag Alloys: Phase Selection and Practical Application

Energy Material Advances
Dendrite formation, contact loss, and continuous formation of the solid electrolyte interphase (SEI) preclude the practical use of the energy-dense lithium (Li) metal.
Yuping Huang, Shiwei Chen, Yu Yang, Zhe-Tao Sun, Xinyu Yu, Chaohong Guan, Runxin Ouyang, Yunlong Guo, Shou-Hang Bo, Hong Zhu   +9 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Application of Two Conditions of Loss of Stability in Analysis of the Tube Bending Process [PDF]

, 2019
In this paper, the derivation of expressions for admissible values of strains and stresses for vertex points of layers subjected to tension during tube bending at bending machines is presented.
Śloderbach, Z., Z. Śloderbach
core   +1 more source

Effect of a flower-like nickel phyllosilicate-containing iron on the thermal stability and flame retardancy of epoxy resin

Journal of Materials Research and Technology, 2020
Flower-like nickel phyllosilicate (Ni-PS) was synthesized via the mild hydrothermal method. The generated Ni-PS containing ferric (Fe@Ni-PS) was then characterized and introduced into epoxy resins (EP) to prepare EP composites.
Shibin Nie, Die Jin, Yuxuan Xu, Chao Han, Xiang Dong, Ji-nian Yang   +5 more
doaj   +1 more source