Results 61 to 70 of about 41,889 (298)

Predictive Model and Software for Inbreeding-Purging Analysis of Pedigreed Populations

open access: yesG3: Genes, Genomes, Genetics, 2016
The inbreeding depression of fitness traits can be a major threat to the survival of populations experiencing inbreeding. However, its accurate prediction requires taking into account the genetic purging induced by inbreeding, which can be achieved using
Aurora García-Dorado   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Purging due to self-fertilization does not prevent accumulation of expansion load.

open access: yesPLoS Genetics, 2023
As species expand their geographic ranges, colonizing populations face novel ecological conditions, such as new environments and limited mates, and suffer from evolutionary consequences of demographic change through bottlenecks and mutation load ...
Leo Zeitler   +2 more
doaj   +1 more source

Pipeline Purging Principles and Practice [PDF]

open access: yes, 1998
Gas purging, a process of displacing one gas by another gas, occurs on a routine basis in the natural gas industry when pipelines are purged into and out of service.
Lambeth, Alan   +4 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Simulasi Sistem Purging Valve Pipa Penyalur Tembakau pada Industri Rokok di PT. Djarum Kudus

open access: yesTechne, 2019
Proses pembuatan rokok di industri rokok memerlukan sistem pneumatic feeding untuk melakukan proses distribusi tembakau. Mesin yang terlibat adalah mesin feeder dan mesin maker. Tembakau sebagai bahan dasar rokok disalurkan melalui pipa dari mesin feeder
Lukas Bambang Setyawan
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Personality characteristics and medical impact of stimulant laxative abuse in eating disorder patients—a pilot study

open access: yesJournal of Eating Disorders, 2021
Background Stimulant laxative abuse as a purging behavior can be profound in those with eating disorders. However, the psychopathology leading to stimulant laxative abuse is poorly understood.
Dennis Gibson   +4 more
doaj   +1 more source

Purging of impure income: a comparative study of the existing purging methodologies [PDF]

open access: yes, 2017
Purpose: The purpose of this paper is to study the concept of purging and present a comparative study of the existing purging methodologies prevailing in the market with a view to evolving a more effective method of capturing the entire impure income to ...
Mohammed, Wasiullah Shaik   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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