Results 71 to 80 of about 45,662 (293)

The moderating role of food cravings in the relationship between weight suppression and eating disorder psychopathology in college students

open access: yesFrontiers in Psychology
Weight suppression (WS), the difference between an individual’s current and highest adult weight, is predictive of eating-related pathology across diagnostic categories and poor eating disorder treatment outcomes, but findings from non-clinical samples ...
Susana Cruz Garcia, Julia M. Hormes
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Must One Indeed Imagine Sisyphus Happy? Recurring Judicial Accountability Rounds as Rule of Law Exceptions in Post-Communist Europe

open access: yesGerman Law Journal
The promise of cleansing judiciaries of judges who are unfit for democracy and rule of law paradigms has been central to judicial reforms for European post-communist countries approaching the Europe they imagined.
Arnisa Tepelija
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Selective purging of human multiple myeloma cells from peripheral blood mononuclear cells: a preliminary study

open access: yes, 2019
A-Jin Lee, Sang-Gyung Kim Department of Laboratory Medicine, Daegu Catholic University School of Medicine, Daegu, Korea Background: High-dose chemotherapy followed by autologous peripheral blood stem-cell transplantation are standards of therapy for ...
Lee AJ, Kim SG
core  

Highly Efficient Flexible-Purging Redundancy Scheme

open access: yes, 2012
[[abstract]]A fault-tolerance technique for flexible-purging redundancy is proposed and designed. The sequence of purging the fault modules is set by 0, 1, 0,... alternately. The flexible-purging redundancy (FPR) scheme with N channels can tolerate N - 1
HAO-YUNG LO;JAMES H. W. TSENG
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Low-Flow Purging and Sampling Guidance

open access: yes, 2003
The procedures in this guidance document are specific to Low-Flow Purging and Sampling (LFPS) of monitor wells in New Jersey. The purpose of Low-Flow Purging and Sampling (LFPS) is to collect groundwater samples from monitor wells that are ...

core   +1 more source

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