Results 41 to 50 of about 1,087,298 (289)

The effect of refined nursing intervention on patients undergoing maintenance hemodialysis in the hemodialysis center during the COVID-19 epidemic

BMC Nursing, 2021
Background The outbreak of novel coronavirus pneumonia has exerted considerable psychological pressure on patients undergoing hemodialysis, resulting in unhealthy psychological emotions.
Qing-Lai Zhang, Shuo Wang, Yue Zhang, Fei Meng   +3 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

HBP21 Alleviates Sepsis-Induced Acute Kidney Injury by Targeting PI3K/AKT-Mediated M1 Macrophage Polarization

Mediators of Inflammation
Conclusion: These findings suggest that HBP21 mitigates S-AKI pathogenesis via PI3K/AKT-mediated M2 macrophage polarization, underscoring its translational potential in renal injury therapy.
Na An, Mingzhi Xu, Ruman Chen, Cuijuan Wang, Yafei Bai   +4 more
doaj   +1 more source

Development of anti-glomerular basement membrane glomerulonephritis during the course of IgA nephropathy: a case report

BMC Nephrology, 2019
Background Anti-glomerular basement membrane (GBM) glomerulonephritis does not usually coexist with another glomerulonephritis such as IgA nephropathy.
Tadasu Kojima, Go Hirose, Shuuhei Komatsu, Taito Oshima, Kentaro Sugisaki, Tomohiro Tomiyasu, Noriko Yoshikawa, Muneharu Yamada, Takashi Oda   +8 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Willingness and influencing factors of adults receiving Hemodialysis to use mobile healthcare apps: a cross-sectional study

BMC Nephrology
Purpose Grounded on the Technology Acceptance Model and integrating theories of perceived risk and trust, this study explores the willingness of adults receiving hemodialysis to use mobile healthcare application services as well as its influencing ...
Jun Xu, Suping Guo, Xintao Yu, Xiaojing Ji   +3 more
doaj   +1 more source

Molecular mechanisms of hydrogen sulfide against uremic accelerated atherosclerosis through cPKCβII/Akt signal pathway

BMC Nephrology, 2019
Background Cardiovascular disease is the most common complication and leading cause of death in maintenance hemodialysis patients. The protection mechanism of hydrogen sulfide (H2S) and the specific role of conventional protein kinase C βII (cPKCβII)/Akt
Ruifang Xiong, Xiangxue Lu, Jinghong Song, Han Li, Shixiang Wang   +4 more
doaj   +1 more source

Integrated management is effective in the prevention and control of COVID-19 in the blood purification center: joint efforts from multiple departments

Renal Replacement Therapy, 2021
Background During the outbreak of new coronavirus pneumonia, many hospitals in China became the designated hospitals for the treatment of new coronavirus pneumonia.
Jinmei Yin, Jun Yin, Zhiwu Tian, Peiqiu Li, Xiaoqiu Chen   +4 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Association between the serum uric acid-to-creatinine ratio and cardiovascular mortality in maintenance hemodialysis patients

Renal Failure
Background Uric acid is a risk factor for death in hemodialysis patients, but its exact role is still unclear. The serum uric acid-to-serum creatinine (SUA/SCr) ratio is a new indicator. This study aimed to clarify the relationship between this indicator
Wanqing Huang, Ning Ding, Yanping Zhang, Dongxia Qiu, Lin Wei, Chen Zhao, Zhuo Ren, Qian Wang, Kaiming Ren, Jiuxu Bai, Ning Cao   +10 more
doaj   +1 more source