Results 81 to 90 of about 2,474,651 (380)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Analysis of the mediating effect of social status perception on professional identity and work engagement of blood purification nurses

open access: yesScientific Reports
To explore the relationship between social status perception, professional identity, and work engagement among nurses involved in blood purification, and to provide a theoretical basis for improving the professional identity and work engagement of blood ...
Jia Wanning   +4 more
doaj   +1 more source

Thrombotic microangiopathy with transiently positive direct Coombs test in an adult with poststreptococcal acute glomerulonephritis: a case report

open access: yesBMC Nephrology, 2022
Background To date, a few case reports have described the association between poststreptococcal acute glomerulonephritis (PSAGN) and hemolytic anemia/thrombocytopenia, both with or without a pathology similar to that of thrombotic microangiopathy (TMA ...
Dan Inoue   +12 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

HBP21 Alleviates Sepsis-Induced Acute Kidney Injury by Targeting PI3K/AKT-Mediated M1 Macrophage Polarization

open access: yesMediators of Inflammation
Conclusion: These findings suggest that HBP21 mitigates S-AKI pathogenesis via PI3K/AKT-mediated M2 macrophage polarization, underscoring its translational potential in renal injury therapy.
Na An   +4 more
doaj   +1 more source

Post-Quantum Key Exchange and Subscriber Identity Encryption in 5G Using ML-KEM (Kyber)

open access: yesInformation
5G addresses user privacy concerns in cellular networking by encrypting a subscriber identifier with elliptic-curve-based encryption and then transmitting it as ciphertext known as a Subscriber Concealed Identifier (SUCI).
Qaiser Khan   +2 more
doaj   +1 more source

Accurate RT-qPCR gene expression analysis on cell culture lysates [PDF]

open access: yes, 2012
Gene expression quantification on cultured cells using the reverse transcription quantitative polymerase chain reaction (RT-qPCR) typically involves an RNA purification step that limits sample processing throughput and precludes parallel analysis of ...
Mestdagh, Pieter   +2 more
core   +2 more sources

SARS-CoV-2 detection using isothermal amplification and a rapid, inexpensive protocol for sample inactivation and purification

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance This work describes the optimization of a sample preparation and detection pipeline for a SARS-CoV-2 diagnostic test that is rapid and does not require specialized equipment.
Brian A. Rabe, C. Cepko
semanticscholar   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Willingness and influencing factors of adults receiving Hemodialysis to use mobile healthcare apps: a cross-sectional study

open access: yesBMC Nephrology
Purpose Grounded on the Technology Acceptance Model and integrating theories of perceived risk and trust, this study explores the willingness of adults receiving hemodialysis to use mobile healthcare application services as well as its influencing ...
Jun Xu   +3 more
doaj   +1 more source

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