Results 211 to 220 of about 304,542 (327)

Radiation‐induced peroxide rupture and its temperature‐dependent repair probed by homogeneous X‐ray irradiation

Acta Crystallographica Section D, EarlyView.
This manuscript investigates the X‐ray‐induced radiolysis of the catalytic C5‐peroxide adduct in urate oxidase crystals, utilizing a top‐hat X‐ray beam to monitor peroxide occupancy across extensive dose series at both 100 K and room temperature. The study reveals a kinetic phase transition where the peroxide decays rapidly via zero‐order kinetics at ...
Symeon Koulas, Soi Bui, Julius B. Kirkegaard, Gleb Bourenkov, Roberto A. Steiner   +4 more
wiley   +1 more source

Implication of xanthine oxidoreductase in oxidative stress-related chronic diseases. [PDF]

Front Endocrinol (Lausanne)
Nelson KL, Voruganti VS.
europepmc   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

Integrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu, Li Sun, Jiao Chen, Jing Wang, Miao Guan, Shixia Xu   +5 more
wiley   +1 more source

PUF, a biflavone monomer, triggers DNA damage through SLC25A15 downregulation and purine metabolic suppression in DLBCL. [PDF]

J Transl Med
Su C, Lu G, Ou L, Liang L, Wang C, He Y, Zeng R, Li Y, Zhou H, Xiao L.   +9 more
europepmc   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

PurK, <i>N</i>⁵-Carboxyaminoimidazole Ribonucleotide Synthetase, an Exocrine Protein Induced by Potato Plants, Influences the Virulence Through Motility Modulation in <i>Pectobacterium brasiliense</i> NJAU180. [PDF]

Microorganisms
Xia L, Zhuo Y, Lin N, Yu N, Che S, Wang C, Yang L, Hu B, Tian Y, Fan J.   +9 more
europepmc   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

Multi-omics analysis reveals the mechanism of verbenalin in treating gout via modulating purine metabolism, gut microbiota, and inflammatory pathways. [PDF]

Front Immunol
Xiao Y, Zhang T, Chen Q, Zhang Y, Chen B, Wang M, Zhang Y, Huang M, Su Y, Guo J.   +9 more
europepmc   +1 more source

Comparative study of blood biochemistry in clinically healthy farmed barramundi (Lates calcarifer) and rainbow trout (Oncorhynchus mykiss) from freshwater recirculating aquaculture systems

Australian Veterinary Journal, EarlyView.
Barramundi (Lates calcarifer) is an economically significant aquaculture species and ranks among Australia's top five farmed finfish. As global production intensifies, understanding the physiology and health of barramundi is essential to support animal welfare and industry profitability.
CY(V) Pang, N Courtman, F Samsing
wiley   +1 more source