Results 191 to 200 of about 245,344 (350)

Biological Activity Profile of Triazolylpurine Nucleosides

The biological activity of novel 2,6-bis-(1,2,3-triazol-1-yl)purine, N6-substituted-2-(1,2,3-triazol-1-yl)adenine and 6-alkyl/arylthio-2-(1,2,3-triazol-1-yl)purine nucleosides were studied.
Petrovska, Ramona, Mandrika, Ilona, Bizdēna, Ērika, Novosjolova, Irina, Kloviņš, Jānis, Turks, Māris   +5 more
core  

Chronic High‐Salt Intake Reprograms Metabolic Homeostasis Driven by Dietary Rice Varieties via Microbial and Metabolite Associations

iMetaMed, EarlyView.
Using a 2% salt diet and a 10‐month feeding to model chronic human sodium exposure, we found that black rice improved glucose tolerance and short‐chain fatty acids, but 2% salt inverted black rice's blood glucose benefits. White rice + 2% salt treatment uniquely increased short‐chain fatty acids.
Xiaofang Li, Fangyang Chen, Ping Chen, Yage Wang, Mengke Yuan, Zhuojun Li, Hao Chen, Zongkang Zhang, Kaikai Li   +8 more
wiley   +1 more source

Associations Between Gut Microbiota Abundance, Dietary Purine Intake, and Fecal Short-Chain Fatty Acids Across the Clinical Spectrum of Hyperuricemia: A Cross-Sectional Study in Mexican Adults. [PDF]

Nutrients
Fuentes-Bello AC, Guevara-Gonzalez KV, Granados-Portillo O, Sánchez-Lozada LG, Jasso-Chávez R, Galeana-Cadena D, Altamirano-Molina E, Herrera-López B, Martínez-Gómez LE, Martínez-Armenta C, López-Jácome LE, Matesanz Sánchez Azcona R, Martínez-García M, Amezcua-Guerra LM, Gutiérrez-Esparza G, Pineda C, Vázquez-Mellado J, López-Reyes AG, Martínez-Nava GA.   +18 more
europepmc   +1 more source

New Achievements in the Chemistry of Triazolyl Purine Nucleosides

Synthesis of novel 2- and 6-alkyl/arylthiopurine derivatives was developed. Reactions were carried out between 2,6-diazidopurine, 2,6-dichloropurine and 2,6-bis-triazolylpurine derivatives and different S-nucleophiles.
Bizdēna, Ērika, Novosjolova, Irina, Turks, Māris   +2 more
core  

Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows

iMetaOmics, EarlyView.
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang, Yangyi Hao, Jiawei Zhang, Yajing Wang, Zhijun Cao, Hongjian Yang, Wei Wang, Shengli Li   +7 more
wiley   +1 more source

Covalently linked purine dimers or trimers and purine-pyrimidine conjugates - analogues of nucleobase-pairs or triplets

, 2002
Covalent analogues of pairs and triplets of nucleobases consisting of purine dimers and trimers and purine-pyrimidine conjugates connected by various types of carbon-linkers (acetylene, diacetylene, vinylene, ethylene, phenylene, benzenetriyl) are ...
Hocek, Michal
core  

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source

Biochemical Remodeling of Purine Metabolism and Lipid Peroxidation Across Thyroid Disease Phenotypes. [PDF]

Metabolites
Bekov E, Ponamareva O, Bakirova R, Molotov-Luchanskiy V, Omarbekova N, Abdikadirova K, Kharin A, Pozdnyakova Y.   +7 more
europepmc   +1 more source

Frontiers in transition‐metal single‐atom electrocatalysts: Design tactics, mechanistic regulation, and electrochemical sensing technologies

InfoMat, EarlyView.
This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao, Bo‐Yu Chen, Yiru Sheng, Haoyuan Song, Linan Zhu, Xiaohan Yang, Yuehe Lin, Wenlei Zhu, Yang Zhou   +8 more
wiley   +1 more source

Gender Differences in the Clinical and Metabolic Manifestations of Anemia in Chronic Heart Failure. [PDF]

J Clin Med
Konysbek Y, Turar A, Molotov-Luchanskiy VB, Ponamareva OA.   +3 more
europepmc   +1 more source