Results 241 to 250 of about 1,617,490 (298)
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Chemistry of Heterocyclic Compounds, 1984
The chlorination of 1,8-dimethyl-7-phenylimidazo[1,2-f]xanthine with an equimolar amount of PCl5 in POCl3 leads to 2,4-dichloro-8-methyl-7-phenylimidazo[1,2-f]-purine. The possibility of substitution of the halogen atoms in reactions with nucleophilic reagents to give various 4-amino and 2,4-diamino derivatives was studied.
S. N. Garmash +4 more
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The chlorination of 1,8-dimethyl-7-phenylimidazo[1,2-f]xanthine with an equimolar amount of PCl5 in POCl3 leads to 2,4-dichloro-8-methyl-7-phenylimidazo[1,2-f]-purine. The possibility of substitution of the halogen atoms in reactions with nucleophilic reagents to give various 4-amino and 2,4-diamino derivatives was studied.
S. N. Garmash +4 more
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Measurement of Purine Derivatives and Creatinine in Urine by HPLC
2004Two HPLC methods to measure the purine derivatives (PD, including allantoin, uric acid, hypoxanthine and xanthine) and creatinine content in urine are described. PD separation and quantification were achieved using two Spherisorb ODS 2 reversed phase columns connected in series (4.6 × 250 mm) and a Spherisorb ODS 2 Waters pre-column and a Perkin Elmer ...
PIANI B, FABRO C, SUSMEL, Piero
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Investigations in the purine series. II. Synthesis of some purine derivatives
Recueil des Travaux Chimiques des Pays-Bas, 1946AbstractSyntheses of xanthine, 3,7‐, 1,3‐ and 1,7‐diethyl‐ and of 3‐ and 7‐monoethyl‐xanthines are described in this ...
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Synthesis of derivatives of purine
Pharmaceutical Chemistry Journal, 1971N. Ya. Bel'kina +3 more
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Purine derivatives as dapk1 inhibitors
2016Derivados de purina como inhibidores de Dapk-1. La presente invención describe una nueva familia de derivados de purina que actúan como inhibidores selectivos de Dapk1. Se describe también el proceso para la obtención de los compuestos farmacéuticos y su uso como medicamento para el tratamiento o la profilaxis de enfermedades que precisan la inhibición
Molina Pineda Infantas, Ignacio Jesús +5 more
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Syntheses in the field of purine derivatives
Pharmaceutical Chemistry Journal, 1973I. M. Ovcharova, E. S. Golovchinskaya
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Purine and pyrimidine derivatives in the Hen's egg
Naturwissenschaften, 1970S, De Boeck, J, Stockx
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Synthesis of purine derivatives of potential immunomodulatory activity.
Bollettino chimico farmaceutico, 2000Moving from the interest as immunomodulatory agent of ST789 was studied the synthesis of series of N9alkylated hypoxanthine and adenine. The synthesis and the chemical physical properties of these derivatives are here described.
E. Pini +3 more
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Tetrahydro-2-pyranyl Derivatives of Purines
The Journal of Organic Chemistry, 1966N, Nagasawa, I, Kumashiro, T, Takenishi
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Hydrolytic degradation of purine derivatives to glycine
Biochimica et Biophysica Acta, 1962R H, LINDSAY, W K, PAIK, P P, COHEN
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