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The potential for biased signalling in the P2Y receptor family of GPCRs
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
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Functional Annotation of Altered Root Metabolites and Metabolic Pathways in Spring Wheat Cultivars Under Varying Salinity and Photoperiod. [PDF]
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The roles of gut microbiota and their metabolites in uric acid-related metabolic diseases: mechanisms and therapeutic targets. [PDF]
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Identification of Novel Small-Molecule Janus Kinase 1 and 2 Inhibitors Through Structure-Based Virtual Screening, <i>In Vitro</i> Assays, and Molecular Dynamics Simulations. [PDF]
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Critical regulatory pathways for the development of sheep myoblasts and the enhancement of cultured meat quality. [PDF]
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