Results 111 to 120 of about 72,751 (304)

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

Open, multi-center randomized research and clinical program MINOTAUROS: intermediate data analysis

open access: yesКардиоваскулярная терапия и профилактика, 2006
Aim. To assess indapamide (Arifon retard) effects on blood pressure (BP), carbohydrate, lipid, purine and electrolyte metabolism in patients with mild arterial hypertension (AH) and metabolic syndrome (MS). Material and methods.
I. E. Chazova, V. B. Mychka
doaj  

Integrated green extraction of phenolic compounds and fermentable sugars from grapefruit peel using ultrasound and enzymatic hydrolysis

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Valorizing sugar‐rich food waste in biorefineries offers a sustainable route to bio‐based products. Grapefruit peel (GP), representing about 50% of the fruit´s weight, is rich in sugars (soluble and insoluble) and polyphenols such as flavonoids.
María del Prado García‐Aparicio   +2 more
wiley   +1 more source

One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression [PDF]

open access: gold
Sara Zirpoli   +7 more
openalex   +1 more source

Cashew Nut Oil Improves Lipid Metabolism and Fat Liver Deposition in High‐Fat Diet‐Fed C57BL/6J Mice

open access: yesLipids, EarlyView.
Thirty C57BL/6J mice were fed a high‐fat diet for 12 weeks to induce metabolic changes. They were then switched to diets containing cashew nut oil, soybean oil, or lard for another 12 weeks. Soybean oil reduced blood glucose, total cholesterol, LDL cholesterol, triglycerides, and liver steatosis.
Marcella Duarte Villas Mishima   +11 more
wiley   +1 more source

Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteria

open access: yesNature Communications
Purines and their derivatives control intracellular energy homeostasis and nucleotide synthesis, and act as signaling molecules. Here, we combine structural and sequence information to define a purine-binding motif that is present in sensor domains of ...
Elizabet Monteagudo-Cascales   +6 more
doaj   +1 more source

Oligodendrocyte Precursor Cells in Demyelination Repair: Mechanisms, Crosstalk, and Therapeutic Frontiers

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy