Results 121 to 130 of about 1,297,457 (342)
Alcohol consumption and incident heart failure in men and women
European Journal of Heart Failure, EarlyView.Alcohol consumption and incident heart failure (HF) in men and women. Abstract Aims Regular heavy alcohol consumption may lead to the development of alcohol‐related cardiomyopathy and symptomatic heart failure (HF) later in life. However, the dose–response relationship between alcohol consumption and risk for incident HF, and whether these associations
Hailun Qin +3 more
wiley +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The Effects of Azathioprine (Imuran) on Purine Synthesis in Clinical Disorders of Purine Metabolism* [PDF]
, 1967 William N. Kelley +2 more
openalex +1 more source
Uric Acid‐Lowering and Anti‐Hyperuricemia Effects of Plant‐Based Nutraceuticals and Foods: A Review
Food Chemistry International, EarlyView.Increased UA production and/or decreased UA secretion cause hyperuricemia. Effects and mechanism of flavonoids in reducing UA are summarized. Terpenoids, saponins, alkaloids, vitamin C, polysaccharides, peptides are effective. Plant‐based foods with UA‐lowering ability are reviewed.
Linwei He, Wenjian Yang, Jianhui Liu
wiley +1 more source
Food Frontiers, EarlyView.This study unveils how ASIV reverses diabetic nephropathy by restoring Gna13‐K363 acetylation and reprogramming purine metabolism. Using spatial metabolomics and acetylproteomics, we identified zonation‐specific purine dysregulation in diabetic kidneys, with ASIV normalizing metabolite distribution (hypoxanthine, cAMP, guanine) and targeting Gna13 ...
Shi Qiu +13 more
wiley +1 more source
Symposium on Gout and other Disorders of Purine Metabolism [PDF]
, 1966 R. W. E. Watts
openalex +1 more source
Wearable biosensors based on molecularly imprinted polymers
FlexMat, EarlyView.Wearable biosensors based on molecularly imprinted polymers (MIPs) provide real‐time, non‐invasive monitoring of key biomarkers. This review highlights the research advances on MIPs‐based biosensors with enhanced selectivity, stability, and adaptability in flexible sensing platforms.
Xiangnan Li +3 more
wiley +1 more source
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, EarlyView.Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis +2 more
wiley +1 more source
Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma
Cancer & MetabolismBackground Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine 27 to methionine (H3K27M).
Erik R. Peterson +20 more
doaj +1 more source