Results 191 to 200 of about 1,297,457 (342)

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

The FEBS Journal, EarlyView.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi, Monica Cozzi, Somayeh Asgharpour, Omar De Bei, Serena Faggiano, Francesco Marchesani, Luca Ronda, Marialaura Marchetti, Eleonora Gianquinto, Mariacristina Failla, Gauthier Trèves, Loretta Lazzarato, Francesca Spyrakis, Barbara Campanini, Emanuela Frangipani, Stefano Bettati   +15 more
wiley   +1 more source

An integrated bioinformatics and machine learning approach to identifying biomarkers connecting parkinson's disease with purine metabolism-related genes. [PDF]

BMC Neurol
Wang Y, Wu D, Zheng M, Yang T.
europepmc   +1 more source

Bipolar mania and epilepsy pathophysiology and treatment may converge in purine metabolism: A new perspective on available evidence. [PDF]

Neuropharmacology, 2023
Daniels SD, Boison D.
europepmc   +1 more source

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

The FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika, Antonia Paić, Ana Novačić, Tea Martinić Cezar, Béatrice Vallée, Renata Teparić, Igor Stuparević, Bojan Žunar   +7 more
wiley   +1 more source

Multi-Omics Analysis Reveals Disturbances of Purine Metabolism and Glutamate Metabolism in the Hippocampus of Lipopolysaccharide-Induced Mouse Model of Depression. [PDF]

Brain Behav
Li WW, Xiao R, Chen XY, Pu JC, Chen JJ, Wang HY, Liu LX, Li D, Zhang YD, Li WX, Xie P.   +10 more
europepmc   +1 more source

cdh23 affects congenital hearing loss through regulating purine metabolism. [PDF]

Front Mol Neurosci, 2023
Yang S, Xie BL, Dong XP, Wang LX, Zhu GH, Wang T, Wu WJ, Lai RS, Tao R, Guan MX, Chen FY, Tan DH, Deng Z, Xie HP, Zeng Y, Xiao ZA, Xie DH.   +16 more
europepmc   +1 more source

Studies on Purine-Pyrimidine Metabolism (1)

, 1992
Kinya Hiroshige, Yasumasa Kunifuji, Masayuki Takasugi, Akio Kuroiwa   +3 more
openalex   +2 more sources

The Leaf Reticulate Mutant dov1 Is Impaired in the First Step of Purine Metabolism [PDF]

, 2012
Christian Rosar, Kerstin Kanonenberg, Arun Nanda, Michael Mielewczik, Andrea Bräutigam, Ondřej Novák, Miroslav Strnad, Achim Walter, Andreas P.M. Weber   +8 more
openalex   +1 more source

In vivo and in silico models of Drosophila for Parkinson's disease

The FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur, Rachel Strazdins, Souvarish Sarkar, Tunahan Çakır   +3 more
wiley   +1 more source

Ultrasound irradiation activates purine metabolism and mitochondrial respiration via the MAPK signaling pathway in myotubes. [PDF]

Biochem Biophys Rep
Ma X, Maeshige N, Yamaguchi A, Fu Y, Xing J, Guo Q, Lin H, Lu F, Kondo H, Fujino H.   +9 more
europepmc   +1 more source