Results 21 to 30 of about 1,370,207 (380)
THE PURINE METABOLISM OF ESCHERICHIA COLI
Journal of Biological Chemistry, 1952 Arthur L. Koch +2 more
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Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential
International Journal of Molecular Sciences, 2023 Purines, such as adenine and guanine, perform several important functions in the cell. They are found in nucleic acids; are structural components of some coenzymes, including NADH and coenzyme A; and have a crucial role in the modulation of energy ...
A. Cicero +5 more
semanticscholar +1 more source
Scientific Reports, 2023 Thyroid eye disease (TED), an autoimmune inflammatory disorder affecting the orbit, exhibits a range of clinical manifestations. While the disease presentation can vary, cases that adhere to a prototypical pattern typically commence with mild symptoms ...
Zixuan Wu +4 more
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Disorder of purine metabolism in the etiopathogenesis of urate nephrolithiasis
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023 Urinary stone disease (USD) is a polyetiological urological disease caused by both exogenous and endogenous factors, including hereditary ones. It is characterized by the appearance of stones in the kidneys and urinary tract, and a tendency to relapse ...
S. I. Vorotyntsev +2 more
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International Journal of Molecular Sciences, 2023 This present study was conducted to provide evidence and an explanation for the apoptosis that occurs in the marine rotifer Brachionus plicatilis when facing 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) stress.
Sai Cao +5 more
semanticscholar +1 more source
A Novel Purine and Uric Metabolism Signature Predicting the Prognosis of Hepatocellular Carcinoma
Frontiers in Genetics, 2022 Background: Hepatocellular carcinoma (HCC) is regarded as one of the most common cancers in the world with a poor prognosis. Patients with HCC often have abnormal purine and uric acid metabolism, but their relationship with prognosis is unclear.Methods ...
Shengjie Yang +5 more
doaj +1 more source
Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism [PDF]
, 2012 To be viable, organisms possess a number of (deoxy)nucleotide phosphohydrolases, which hydrolyze these nucleotides removing them from the active NTP and dNTP pools. Deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP,
O.W. Davies +3 more
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Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data
Frontiers in Molecular Neuroscience, 2023 IntroductionPrevious studies have suggested that the dysregulation of purine metabolism may be associated with autism spectrum disorder (ASD). Here, we adopted metabolomics and transcriptomics to verify and explore the underlying molecular mechanism of ...
Si Dai +5 more
doaj +1 more source
Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation
Zoological Research, 2022 Many mammals risk damage from oxidative stress stemming from frequent dives (i.e., cycles of ischemia/reperfusion and hypoxia/reoxygenation), high altitude and subterranean environments, or powered flight.
Ran Tian +5 more
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Altered purine metabolism at reperfusion affects clinical outcome in lung transplantation
Thorax, 2022 Introduction Lung transplantation is an established treatment for patients with end-stage lung disease. However, ischaemia reperfusion injury remains a barrier to achieving better survival outcomes.
C. Baciu +5 more
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