Results 21 to 30 of about 73,159 (260)
Frontiers in Microbiology, 2023 A small subpopulation of Vibrio splendidus AJ01 that was exposed to tetracycline at 10 times the minimal inhibitory concentration (MIC) still survived, named tetracycline-induced persister cells in our previous work.
Yanan Li +5 more
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Yeast to Study Human Purine Metabolism Diseases
Cells, 2019 Purine nucleotides are involved in a multitude of cellular processes, and the dysfunction of purine metabolism has drastic physiological and pathological consequences.
Bertrand Daignan-Fornier, Benoît Pinson
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Computer simulation of purine metabolism [PDF]
European Journal of Biochemistry, 1984 A computer model of purine metabolism, including catabolism, salvage pathways and interconversion among nucleotides, is given. Steady‐state rate equations corresponding to metabolic enzymes are written based on information from the literature about their kinetic behaviour.
R, Franco, E I, Canela
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Purine metabolism in Methanococcus vannielii [PDF]
Journal of Bacteriology, 1993 Methanococcus vannielii is capable of degrading purines to the extent that each of these purines may serve as the sole nitrogen source for growth. Results presented here demonstrate that purine degradation by M. vannielii is accomplished by a route similar to that described for clostridia.
E, DeMoll, T, Auffenberg
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Purine Metabolism and Rett Syndrome
Pediatric Neurology Briefs, 1996 Levels of purine and pyridine nucleotides and their metabolites were determined in erythrocytes and plasma of 31 Rett pattients and 17 age-matched controls at the Departments of Molecular Biology and Child Psychiatry, University of Siena, Children’s ...
J Gordon Millichap
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Purine and pyrimidine metabolism [PDF]
Proceedings of the Nutrition Society, 1982 The pathways of purine biosynthesis and degradation have been elucidated during the last 30 years; the regulation of the mechanisms involved is not yet fully understood, particularly with respect to quantitative aspects. Research into inborn errors of purine metabolism has provided valuable insights into purine synthesis and salvage pathways. Nutrition
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Disorders of purine biosynthesis metabolism
Molecular Genetics and Metabolism, 2022 Purines are essential molecules that are components of vital biomolecules, such as nucleic acids, coenzymes, signaling molecules, as well as energy transfer molecules. The de novo biosynthesis pathway starts from phosphoribosylpyrophosphate (PRPP) and eventually leads to the synthesis of inosine monophosphate (IMP) by means of 10 sequential steps ...
Dewulf, Joseph P +2 more
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Purine metabolism promotes radioresistance and is a therapeutic target in glioblastoma
Molecular & Cellular Oncology, 2020 Profound intratumoral genomic heterogeneity has limited the ability of targeted therapies to overcome therapy resistance in glioblastoma. We have defined purine metabolism as a key mediator of DNA repair and radiation resistance in glioblastoma.
Weihua Zhou, Daniel R Wahl
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A circular network of purine metabolism as coregulators of dilated cardiomyopathy
Journal of Translational Medicine, 2022 Background The crosstalk of purine biosynthesis and metabolism exists to balance the cell energy production, proliferation, survival and cytoplasmic environment stability, but disorganized mechanics of with respect to developing heart failure (HF) is ...
Ge Wang +7 more
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Ecotoxicology and Environmental Safety, 2023 Cadmium (Cd) exposure has been associated with the development of enterohepatic circulation disorders and hyperuricemia, but the possible contribution of chronic low-dose Cd exposure to disease progression is still need to be explored.
Hui Zhang +11 more
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