Results 31 to 40 of about 1,551,682 (283)

Metabolism-Related Prognostic Biomarkers, Purine Metabolism and Anti-Tumor Immunity in Colon Adenocarcinoma

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: Metabolic reprogramming provides a new perspective for understanding cancer. The targeting of dysregulated metabolic pathways may help to reprogram the immune status of the tumor microenvironment (TME), thereby increasing the effectiveness of
Hui Liu   +4 more
doaj   +1 more source

PECULIARITIES OF PURINE METABOLISM AND LIPID PEROXIDATION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study purine metabolism and lipid peroxidation in patients with acute myocardial infarction with ST segment elevation (STEMI) in dependence on severity of acute heart failure (AHF). To evaluate effects of thrombolytic therapy on purine metabolism
E. V. Horolets   +3 more
doaj   +1 more source

Gut bacterial metabolism contributes to host global purine homeostasis

open access: yesCell Host and Microbe, 2023
SUMMARY The microbes and microbial pathways that influence host inflammatory disease progression remain largely undefined. Here we show that variation in atherosclerosis burden is partially driven by gut microbiota and is associated with circulating ...
K. Kasahara   +8 more
semanticscholar   +1 more source

The need for purine examination on fisherman

open access: yesJurnal Teknologi Laboratorium, 2021
The need for purine check on Fisherman is important because when the fisherman excess consuming highly purine contained in the food in a long rime periode will cause purine metabolism disorder and can lead to purine deposition  in  joint tissue and ...
Ketrina Konoralma   +5 more
doaj   +1 more source

Altered purine metabolism at reperfusion affects clinical outcome in lung transplantation

open access: yesThorax, 2022
Introduction Lung transplantation is an established treatment for patients with end-stage lung disease. However, ischaemia reperfusion injury remains a barrier to achieving better survival outcomes.
C. Baciu   +5 more
semanticscholar   +1 more source

Metabolism drives macrophage heterogeneity in the tumor microenvironment

open access: yesCell Reports, 2022
Summary: Tumor-associated macrophages (TAMs) are a major cellular component in the tumor microenvironment (TME). However, the relationship between the phenotype and metabolic pattern of TAMs remains poorly understood.
Shasha Li   +15 more
doaj   +1 more source

Stage-specific regulation of purine metabolism during infectious growth and sexual reproduction in Fusarium graminearum.

open access: yesNew Phytologist, 2021
Ascospores generated during sexual reproduction are the primary inoculum for the wheat scab fungus Fusarium graminearum. Purine metabolism is known to play important roles in fungal pathogens but its lifecycle stage-specific regulation is unclear.
Manli Sun   +9 more
semanticscholar   +1 more source

Purine and pyrimidine metabolism [PDF]

open access: yesProceedings of the Nutrition Society, 1982
The pathways of purine biosynthesis and degradation have been elucidated during the last 30 years; the regulation of the mechanisms involved is not yet fully understood, particularly with respect to quantitative aspects. Research into inborn errors of purine metabolism has provided valuable insights into purine synthesis and salvage pathways. Nutrition
openaire   +2 more sources

Features and relationships of metabolic syndrome components in men with androgen deficiency. Part 2. Disorders of carbohydrate and purine metabolism. Retrospective study data

open access: yesАкушерство, гинекология и репродукция, 2022
Introduction. Currently, few epidemiological data on a relation between impaired purine and carbohydrate metabolism and testosterone deficiency in overweight men due to adipose tissue and metabolic syndrome (MS) are available.Aim: to study relationships ...
Z. Sh. Pavlova, V. Yu. Grevina
doaj   +1 more source

Jia Wei Xiao Yao San ameliorates chronic stress-induced depression-like behaviors in mice by regulating the gut microbiome and brain metabolome in relation to purine metabolism.

open access: yesPhytomedicine, 2022
BACKGROUND The pathogenesis of depression remains largely unknown. Accumulating evidence demonstrates the existence of a complex relationship between gut microbiome composition and brain functions.
Shuai Ji   +11 more
semanticscholar   +1 more source

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