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The Role of Probiotics in Purine Metabolism, Hyperuricemia and Gout: Mechanisms and Interventions
Food reviews international (Print), 2021Hyperuricemia and gout are metabolic diseases characterized with high serum urate and impact human health significantly. Although some drugs have been developed to treat gout, hyperuricemia represents a substantial health problem.
Armachius James +3 more
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New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.
American Journal of Physiology. Endocrinology and Metabolism, 2020Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
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FRUCTOSE AND PURINE METABOLISM
Acta Medica Scandinavica, 1972Abstract.The interactions between fructose and purine metabolism are reviewed. Hyperuricemia and increased production of uric acid after fructose administration have been documented in man as well as in the rat. These effects appear to be dependent on the rapid phosphorylation of fructose, mainly in the liver.
K O, Raivio, M, Kekomäki, P, Mäenpää
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Purine Metabolism in Trypanosomatids*
The Journal of Protozoology, 1979SYNOPSIS. Purine nucleotide biosynthesis was studied in culture forms of Trypanosoma cruzi strain Y, Crithidia deanei (a reduviid trypanosomatid with an endosymbiote) and an aposymbiotic strain of C. deanei (obtained by curing C. deanei with chloramphenicol).
C R, Ceron +4 more
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Environmental Science and Technology, 2020
Parabens are widely used as common preservatives in pharmaceutical and cosmetic industries. Exposure to parabens has been found to be associated with metabolic alterations of human and the increased risk of metabolic disease, such as diabetes.
Hongzhi Zhao +9 more
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Parabens are widely used as common preservatives in pharmaceutical and cosmetic industries. Exposure to parabens has been found to be associated with metabolic alterations of human and the increased risk of metabolic disease, such as diabetes.
Hongzhi Zhao +9 more
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Biochemical Society Transactions, 1981
Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Purine Metabolism in Feline Lymphomas
Veterinary Pathology, 1990Deficiency of the purine metabolic enzyme adenosine deaminase causes severe immunodeficiency. Retroviruses have been reported to decrease the activity of adenosine deaminase, and many retroviruses, including feline leukemia virus, cause immunodeficiency.
E A, Copelan +3 more
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Purine and Pyrimidine Metabolism
2013Purine and pyrimidine nucleotides are essential for a vast number of biological processes such as RNA and DNA synthesis and as a component of high-energy nucleotides, e.g., adenosine triphosphate. Polygenic and Mendelian diseases are associated with altered purine and pyrimidine metabolism; thus, the genes associated with gout have only minor effects ...
Kamatani, Naoyuki +3 more
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Purine metabolism in Schistosoma mansoni
International Journal for Parasitology, 1972Abstract Schistosoma mansoni has been found to have a spectrum of purine nucleotides which is similar, but not identical to mammalian cells. The principal component of this system is ATP, which is present at a level of about 5·5 × 10 −9 moles/mg worm pairs.
A W, Senft +3 more
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Expert Opinion on Drug Metabolism & Toxicology, 2020
Objectives Rifampin (RIF), isoniazid (INH) and pyrazinamide (PZA) are essential components of the short-term first-line anti-tuberculosis (anti-TB) chemotherapy regimen and can cause hepatotoxicity.
Linsheng Liu +7 more
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Objectives Rifampin (RIF), isoniazid (INH) and pyrazinamide (PZA) are essential components of the short-term first-line anti-tuberculosis (anti-TB) chemotherapy regimen and can cause hepatotoxicity.
Linsheng Liu +7 more
semanticscholar +1 more source