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Metabolic and genetic factors affecting the productivity of pyrimidine nucleoside in [PDF]
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Erster Ringversuch zur Bestimmung der Konzentrationen von L-trijodthyronin (T3) und L-Thyroxin (T4) im Serum [PDF]
Horn, K.+2 more
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In Vitro Immunomodulatory Activity of a Transition-State Analog Inhibitor of Human Purine Nucleoside Phosphorylase in Cutaneous Leishmaniasis. [PDF]
Carvalho NB+10 more
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Coapplication of Adenine with Inosine or Guanosine Supports Rapid ATP Restoration by ATP-deprived Cultured Primary Astrocytes. [PDF]
Karger G, Dringen R.
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Symmetric Nucleosides as Potent Purine Nucleoside Phosphorylase Inhibitors.
The Journal of Physical Chemistry B, 2021Nucleic acids are one of the most enigmatic biomolecules crucial to several biological processes. Nucleic acid-protein interactions are vital for the coordinated and controlled functioning of a cell, leading to the design of several nucleoside/nucleotide
Pradeep Pant, A. Pathak, B. Jayaram
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Mutations in purine nucleoside phosphorylase deficiency
Human Mutation, 1997Purine nucleoside phosphorylase deficiency is an inherited disease of purine metabolism characterized clinically as combined immunodeficiency. The molecular defects have been published for 4 different alleles in 3 patients. We report four new mutations including two amino acid substitutions, A174P and G190V, a single codon deletion, delta I129, and a ...
Harold R. Collard+9 more
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Purine nucleoside phosphorylase of chicken liver
Biochimica et Biophysica Acta (BBA) - Enzymology, 1971Abstract Purine nucleoside phosphorylase (purine nucleoside:orthophosphate ribosyltransferase, EC 2.4.2.1) has been purified 125-fold from the homogenate of chicken livers and some of the properties of the purified enzyme have been studied. This enzyme had a pH optimum at around 6.o. At high substrate levels of inosine the reaction rate was increased,
Keizo Tsushima+2 more
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