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Old Doubts From a New Perspective: Oral Versus Subcutaneous Methotrexate

International Journal of Dermatology, Volume 64, Issue 9, Page 1535-1537, September 2025.
Laura Kiss, Rolland Gyulai
wiley   +1 more source

Single-Cell and Spatial Transcriptomics Explore Purine Metabolism-Related Prognostic Risk Model and Tumor Immune Microenvironment Modulation in Ovarian Cancer. [PDF]

Hum Mutat
Liu Y, Geng R, Zhao S, Yang J, Liu J, Zheng Y, Tang W.   +6 more
europepmc   +1 more source

Synthesis of a Pseudocytidine Nucleoside to Form a Stable and Selective Base Pair with Iso-guanosine in RNA. [PDF]

Org Lett
Miyahara R, Taniguchi Y.
europepmc   +1 more source

Landscape of targets within nucleoside metabolism for the modification of immune responses. [PDF]

Front Oncol
Dunderdale EM, Abt ER.
europepmc   +1 more source

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Purine nucleotide catabolism in placenta

American Journal of Obstetrics and Gynecology, 1964
Abstract Soluble extracts were utilized to delineate the catabolic pathways of purine 2′,3′- and 5′-ribonucleoside monophosphates in human placenta and to measure the relative activities of the enzymes involved. Derivatives of adenine and hypoxanthine are converted to hypoxanthine, and derivatives of guanine are converted to xanthine.
Robert C. Baldridge, T.Terry Hayashi, Donald L. Kimmel, Peter S. Olmsted   +3 more
openaire   +3 more sources

Purine nucleotide cyclases in the malaria parasite [PDF]

Trends in Parasitology, 2004
Cells use a variety of signal transduction pathways to coordinate their responses to changes in both the extracellular and intracellular environment. Activation of these pathways is often receptor mediated, resulting in the synthesis of second messenger molecules such as cAMP and cGMP.
David A. Baker, John M. Kelly
openaire   +2 more sources

Alterations in purine nucleotide pyrophosphorylases and resistance to purine analogues

Biochimica et Biophysica Acta, 1961
Abstract Resistance to purine analogues in mutants isolated from Salmonella typhimurium , strain LT-2 , resulted in the loss of specific purine nucleotide pyrophosphorylases. Thus, mutants resistant to 2,6-diaminopurine, 6-mercaptopurine, and 8-azaguanine lacked adenylic, inosinic and guanylic pyrophosphorylases, respectively. The mutants resistant
Joseph S. Gots, Gurudutt P. Kalle
openaire   +3 more sources