Results 281 to 290 of about 661,667 (342)
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De Novo Purine Nucleotide Biosynthesis
1992This chapter reviews current understanding of de novo purine nucleotide synthesis in Bacillus subtilis,with emphasis on recent developments in understanding gene organization and regulation and on the distinctive structural features of two enzymes of the pathway.
H, Zalkin, J E, Dixon
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Purine Nucleotide Catabolism in Rat Liver
2006The higher specific radioactivity of ALL in comparison to UA, which are observed after administration of labelled precursors, changed when, oxonic acid and allopurinol, inhibitors of UA and ALL formation were administrated. To interpret these results, it is worth while to recall that nucleotide metabolism can be represented as a complex sequence ...
Marinello E. +5 more
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Nucleic Acids, Purines, Pyrimidines (Nucleotide Synthesis)
Annual Review of Biochemistry, 1959period and has been inc luded. The factors involved in nucleotide and nu cleic acid synthesis in vivo have also been discussed. With certain excep tions, extensive discussion has been omitted of topics related to the partici tion of nucleotides in other metabolic processes to be revie wed in this vol ume, such as protein synthesis and carbohydrate ...
S C, HARTMAN, J M, BUCHANAN
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Purine nucleotide biosynthesis in gastrointestinal mucosa
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973Abstract Two methods were used to elucidate the relative dependence of intestinal mucosa on the alternative pathways of purine nucleotide biosynthesis. While salvage activity was high, there was no evidence of active de novo purine synthesis by either method, suggesting that intestinal mucosa is dependent on salvage pathway activity for the provision
A M, Mackinnon, D J, Deller
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3 Purine, Purine Nucleoside, and Purine Nucleotide Aminohydrolases
1971Publisher Summary This chapter discusses the chemical significance of adenosine aminohydrolase, 5′-adenylic acid aminohydrolase, adenine nucleoside, nucleotide aminohydrolase, guanine aminohydrolase, and guanosine aminohydrolase. The partially purified adenine aminohydrolase from Azotobacter vinelandii catalyzes the anaerobic conversion of adenine ...
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Alterations in purine nucleotide pyrophosphorylases and resistance to purine analogues
Biochimica et Biophysica Acta, 1961Abstract Resistance to purine analogues in mutants isolated from Salmonella typhimurium , strain LT-2 , resulted in the loss of specific purine nucleotide pyrophosphorylases. Thus, mutants resistant to 2,6-diaminopurine, 6-mercaptopurine, and 8-azaguanine lacked adenylic, inosinic and guanylic pyrophosphorylases, respectively. The mutants resistant
G P, KALLE, J S, GOTS
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Purine Nucleotide Synthesis during Terminal Differentiation
1989A number of human myeloid leukemia cell lines have been established which can not only be maintained as immature blast cells in continuous, self-renewing culture but also be induced to undergo maturation toward either the myeloid or monocytic phenotype1).
H, Tsutani +5 more
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Purine Nucleotide Interconversions
1978The various reactions of purine ribonucleotide synthesis result in the formation of adenylate, inosinate, and guanylate; xanthylate may also be formed, but this seems to be a quantitatively minor process in most mammalian cells. These purine ribonucleoside monophosphates can be metabolized in several different ways; these processes can in general be ...
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Structural basis for the binding of DNP and purine nucleotides onto UCP1
Nature, 2023Yunlu Kang, Lei Chen
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Thermodynamics of the purine nucleotide cycle
Biophysical Chemistry, 2006Since the standard Gibbs energies of formation are known for all the species in the purine nucleotide cycle at 298.15 K, the functions of pH and ionic strength that yield the standard transformed Gibbs energies of formation of the ten reactants can be calculated.
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