Results 11 to 20 of about 1,417,283 (133)

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

open access: yes, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Tasker, Paul N.   +3 more
core   +4 more sources

Pharmacological and Molecular Characterisation of P2Y Receptors in Endothelial and Epithelial Cells [PDF]

open access: yes, 2007
Submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyIn light of the significant modulation of receptor activity previously shown by a peptide (designated L247), designed to mimic ...
D’Souza, Vijay Kenneth
core   +3 more sources

Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders

open access: yesFrontiers in Pharmacology, 2017
Extracellular nucleosides and nucleotides, such as adenosine and adenosine triphosphate (ATP), are involved in many physiological and pathological processes in adipose tissue (AT).
Marco Tozzi, Ivana Novak
doaj   +1 more source

Ontogeny of purinergic receptor-regulated Ca2+ signaling in mouse cortical collecting duct epithelium [PDF]

open access: yes, 2002
Changes in ATP-induced increase in {[}Ca2+], during collecting duct ontogeny were studied in primary monolayer cultures of mouse ureteric bud (UB) and cortical collecting duct (CCD) cells by Fura-PE3 fluorescence ratio imaging.
Tschop, J.   +4 more
core   +1 more source

Purinergic mechanosensory transduction and visceral pain [PDF]

open access: yes, 2009
In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain.
Geoffrey Burnstock   +2 more
core   +1 more source

Adenosine Receptor Agonists Exhibit Anti-Platelet Effects and the Potential to Overcome Resistance to P2Y12 Receptor Antagonists

open access: yesMolecules, 2019
Large inter-individual variation in platelet response to endogenous agonists and pharmacological agents, including resistance to antiplatelet therapy, prompts a search for novel platelet inhibitors and development new antithrombotic strategies.
Nina Wolska   +7 more
doaj   +1 more source

The role of purinergic receptors in stem cell differentiation

open access: yesComputational and Structural Biotechnology Journal, 2015
A major challenge modern society has to face is the increasing need for tissue regeneration due to degenerative diseases or tumors, but also accidents or warlike conflicts.
Constanze Kaebisch   +3 more
doaj   +1 more source

Purinergic signaling in the gastrointestinal tract [PDF]

open access: yes, 2011
Geoffrey Burnstock completed a BSc at King's College London and a PhD at University College London. He held postdoctoral fellowships with Wilhelm Feldberg (National Institute for Medical Research), Edith Bülbring (University of Oxford) and C.
Geoffrey Burnstock, Burnstock, G
core   +1 more source

Purinergic Receptors in Ocular Inflammation

open access: yesMediators of Inflammation, 2014
Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease.
Ana Guzman-Aranguez   +3 more
doaj   +1 more source

Cascade bioassay evidence for the existence of urothelium-derived inhibitory factor in Guinea pig urinary bladder.

open access: yesPLoS ONE, 2014
Our aim was to investigate whether guinea pig urothelium-derived bioactivities compatible with the existence of urothelium-derived inhibitory factor could be demonstrated by in vitro serial bioassay and whether purinergic P1 receptor agonists, nitric ...
Na N Guan   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy