Results 71 to 80 of about 1,295,695 (149)

Purinergic signalling: past, present and future [PDF]

, 2009
The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
G. Burnstock, Burnstock, G
core  

Expression of purinergic P2Y receptor subtypes by INS-1 insulinoma beta-cells: a molecular and binding characterization.

, 2007
National audiencePurinergic P2Y-receptor agonists amplify glucose-induced insulin secretion from pancreatic beta-cells, thus offering new opportunities for the treatment of type 2 diabetes.
Gross, René, Petit, Pierre, Vignon, Jacques, Lajoix, Anne-Dominique, Filhol, Romain, Lugo-Garcia, Laura   +5 more
core   +1 more source

Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification [PDF]

, 2012
Purinergic signaling has a crucial role in different vascular processes. The endothelial-derived vasoconstrictor uridine adenosine tetraphosphate (Up4A) is a potent activator of the purinoceptor P2Y and is released under pathological conditions.
van der Giet, Markus, Joachim Jankowski, Prüfer, Jasmin, Mirjam Schuchardt, Vera Jankowski, Prüfer, Nicole, Markus Tölle, Schuchardt, Mirjam, Jasmin Prüfer, Huang, Tao, Tao Huang, Tölle, Markus, Nicole Prüfer, Walter Zidek, Markus van der Giet, Jankowski, Joachim, Jankowski, Vera, Zidek, Walter   +17 more
core   +1 more source

Adenosine Triphosphate Induced P2Y(2) Receptor Activation Induces Proinflammatory Cytokine Release in Uroepithelial Cells

, 2012
PURPOSE: We characterized and identified the uroepithelial P2 receptor responsible for adenosine triphosphate mediated release of the cytokines interleukin-8 and 6.MATERIALS AND METHODS: The human renal epithelial cell line A498 (ATCC™) was cultured and ...
Kruse, Robert, Kruse, Robert,, Persson, Katarina,, Säve, Susanne,   +3 more
core   +1 more source

The P2X receptor mediated regulation of inhibitory synaptic transmission [PDF]

In the central nervous system ATP can be released by neurons and glial cells through similar pathways as other neurotransmitters. Extracellular ATP targets P2X purinoreceptors, causing an influx of Ca2+ ions which transmit very important messages for ...
Andrew-Adiamah, Jemma
core  

Heterogeneity of P2u- and P2y-purinergic receptor regulation of phospholipases in MDCK cells

, 1996
We have characterized the signaling pathways of purinergic receptors present on the renal epithelial cell line, Madin-Darby canine kidney (MDCK, D1 subclone).
M. Xing, P. A. Insel, R. J. Hughes, B. L. Firestein, C. U. Corvera   +4 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Investigation of P2Y₁ and P2Y₁₂ receptor heterodimerisation

, 2014
Heterodimerisation of G-Protein Coupled Receptors (GPCR) is an emerging research niche with implications for understanding signalling, pathophysiology and development of new drug targets.
Naughton, Roger
core   +2 more sources

Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X(1)-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y(1) and P2Y(12) receptor activation

, 2010
Toll-like receptor 2 (TLR2), which recognise and respond to conserved microbial pathogen-associated molecular patterns, is expressed on the platelet surface. Furthermore, it has recently been shown that the TLR2/1 agonist Pam(3)CSK(4) stimulates platelet
Skoglund, Caroline,, Lerm, Maria,, Grenegård, Magnus,, Bengtsson, Torbjörn,, Kälvegren, Hanna,, Helldahl, Christian,   +5 more
core   +1 more source

Interaction between purinergic signalling and purinergic modulators with skin wound repair effectors: a systematic review of preclinical in vivo models. [PDF]

Purinergic Signal
Pelinsari SM, Goncalves RV, da Silva Mattosinhos P, Sarandy MM, Vilela EF, Novaes RD.   +5 more
europepmc   +1 more source