Results 211 to 220 of about 2,316,796 (350)

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, Volume 603, Issue 15, Page 4255-4291, 1 August 2025.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

Altered purinergic receptor expression in the frontal cortex in schizophrenia. [PDF]

Schizophrenia (Heidelb), 2022
Alnafisah R, Lundh A, Asah SM, Hoeflinger J, Wolfinger A, Hamoud AR, McCullumsmith RE, O'Donovan SM.   +7 more
europepmc   +1 more source

P2-Purinergic Receptor-mediated Accumulation of cAMP in Calf Vascular Smooth Muscle Cells.

, 1991
Shusuke Tada, Fumikazu Okajima, Youji Mitsui, Yoichi Kondo, Michio Ui   +4 more
openalex   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, Volume 603, Issue 15, Page 4237-4253, 1 August 2025.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Inhibition of Galectins and the P2X7 Purinergic Receptor as a Therapeutic Approach in the Neurovascular Inflammation of Diabetic Retinopathy. [PDF]

Int J Mol Sci, 2023
Lepre CC, Russo M, Trotta MC, Petrillo F, D'Agostino FA, Gaudino G, D'Amico G, Campitiello MR, Crisci E, Nicoletti M, Gesualdo C, Simonelli F, D'Amico M, Hermenean A, Rossi S.   +14 more
europepmc   +1 more source

Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling

The Journal of Physiology, Volume 603, Issue 15, Page 4329-4344, 1 August 2025.
Abstract figure legend Sphingosine‐1‐phosphate (S1P) binds to Gi protein‐coupled receptor S1PR1. Upon S1PR1 activation, Gβγ is released from the Gαi‐Gβγ heterotrimer, allowing it to recruit phospholipase Cβ (PLCβ) to the plasma membrane. PLCβ cleaves phosphatidylinositol‐4,5‐bisphosphate (PIP2) into inositol trisphosphate (IP3) and diacylglycerol (DAG).
Yulia Kostritskaia, Sumaira Pervaiz, Anna Klemmer, Malte Klüssendorf, Tobias Stauber   +4 more
wiley   +1 more source

Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells

Molecular Pharmacology, 2017
Wayne Stallaert, E. T. van der Westhuizen, Anne-Marie Schönegge, Bianca Plouffe, M. Hogue, V. Lukashova, A. Inoue, S. Ishida, J. Aoki, C. Le Gouill, M. Bouvier   +10 more
semanticscholar   +1 more source

Characterization of purinergic receptor expression in ARPKD cystic epithelia

Purinergic Signalling Purinergic Signalling, 2018
O. Palygin, D. Ilatovskaya, V. Levchenko, C. Klemens, Lashodya V. Dissanayake, A. Williams, T. Pavlov, A. Staruschenko   +7 more
semanticscholar   +1 more source

Neurotransmitter signaling in white matter [PDF]

, 2014
Butt, Arthur M., Fern, Robert F., Matute, Carlos   +2 more
core   +1 more source

Modulation of Phagocytosis by P2-Purinergic Receptors in Mouse Peritoneal Macrophages.

, 1995
Mitsuyuki Ichinose
openalex   +2 more sources