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Purinergic Signaling in the Airways
Pharmacological Reviews, 2012Evidence for a significant role and impact of purinergic signaling in normal and diseased airways is now beyond dispute. The present review intends to provide the current state of knowledge of the involvement of purinergic pathways in the upper and lower airways and lungs, thereby differentiating the involvement of different tissues, such as the ...
Burnstock, Geoffrey +3 more
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Purinergic Signaling in Glioma Progression
2012Among the pathological alterations that give tumor cells invasive potential, purinergic signaling is emerging as an important component. Studies performed in in vitro, in vivo and ex vivo glioma models indicate that alterations in the purinergic signaling are involved in the progression of these tumors.
Elizandra, Braganhol +3 more
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Introduction to Purinergic Signaling
2019Purinergic signaling was proposed in 1972, after it was demonstrated that adenosine 5'-triphosphate (ATP) was a transmitter in nonadrenergic, noncholinergic inhibitory nerves supplying the guinea-pig taenia coli. Later, ATP was identified as an excitatory cotransmitter in sympathetic and parasympathetic nerves, and it is now apparent that ATP acts as a
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Purinergic signalling: an experimental perspective
Journal of the Autonomic Nervous System, 2000Investigation of the multiple roles of extracellular nucleotides in the cochlea has developed from analysis of ATP-activated conductances in single sensory hair cells. Molecular probes such as radiolabelled ATP analogues and radiolabelled mRNA for ATP-gated ion channel subunits (P2X receptors) rapidly revealed the extensive nature of ATP signalling in ...
G D, Housley, P R, Thorne
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Editorial - Purinergic signalling: 50 years
NeuropharmacologyThe function of almost all cells of the human and animal body is synchronized by purinergic/pyrimidinergic extracellular signalling molecules. This network activity is especially efficient in the central and peripheral nervous systems, driven by secretion of the (co)transmitter ATP (including its enzymatic degradation products ADP, AMP, and adenosine),
Illes, Peter +2 more
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Introduction to Purinergic Signalling in the Brain.
Advances in Experimental Medicine and Biology, 2020G. Burnstock
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Reactive oxygen species signalling in plant stress responses
Nature Reviews Molecular Cell Biology, 2022Ron Mittler +2 more
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Interplay between mechanics and signalling in regulating cell fate
Nature Reviews Molecular Cell Biology, 2022Ewa K Paluch +2 more
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