Purinergic signalling - Open Access .click

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2016
Purinergic signalling is a complex and evolutionarily conserved mechanism of extracellular communication involved in many physiological and pathological functions. The complexity arises from a large number of purine receptor subtypes and multiple endogenous purine receptor ligands (including ATP, ADP, UTP, UDP UDP-glucose and adenosine) which can be ...
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Introduction to Purinergic Signalling in the Brain

2012
ATP is a cotransmitter with glutamate, noradrenaline, GABA, acetylcholine and dopamine in the brain. There is a widespread presence of both adenosine (P1) and P2 nucleotide receptors in the brain on both neurons and glial cells. Adenosine receptors play a major role in presynaptic neuromodulation, while P2X ionotropic receptors are involved in fast ...
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Purinergic signaling at immunological synapses

Journal of the Autonomic Nervous System, 2000
The early studies and hypotheses of Geoffrey Burnstock catalyzed intensive characterization of roles for nucleotides and P2 nucleotide receptors in neurotransmission and neuromodulation. These latter analyses have focused on the mechanisms of nucleotide release and action in the microenvironments of nerve endings and synapses.
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Purinergic signalling in cancer therapeutic resistance: From mechanisms to targeting strategies

Drug Resistance Updates, 2023
Yih-Cherng Liou +2 more
exaly

Interplay between purinergic signalling and extracellular vesicles in health and disease

Biochemical Pharmacology, 2022
Juan Pablo Rigalli, Joost G J Hoenderop
exaly

Exploration of the link between gut microbiota and purinergic signalling

Purinergic Signalling, 2022
Bowen Liu, Leng Ping
exaly

MicroRNA: Crucial modulator in purinergic signalling involved diseases

Purinergic Signalling, 2022
Jing Guo, Shu-Guang Yu, Hai-Yan Yin
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The purinergic signalling and inflammation in the pathogenesis and progression of diabetes: key factors and therapeutic targets

Inflammation Research, 2022
Andreia Machado Cardoso
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Purinergic signalling and disorders of the central nervous system

Nature Reviews Drug Discovery, 2008
, Burnstock Geoffrey
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