Results 121 to 130 of about 99,040 (285)

Covalent Attachment of a Platinum(II) Complex inside DNA Duplexes

open access: yesChemistryEurope, EarlyView.
Oxidative addition is used for the site‐specific incorporation of an organometallic PtII complex as an artificial nucleobase into a DNA duplex. The platination stabilizes the duplex and confers it with phosphorescence. An organometallic phosphorescent PtII complex is introduced into DNA duplexes via oxidative addition to a tailor‐made artificial ...
Tim Schäfer   +6 more
wiley   +1 more source

Caffeine Content Assessment in Beverages and Food Supplements: Regulatory Challenges and Health Implications

open access: yesChemFoodChem, EarlyView.
ABSTRACT This study presents an analysis of caffeine content in food supplements and evaluates current regulatory frameworks against established safety guidelines. High‐caffeine products, particularly sports, and food supplements, were assessed for compliance with the safety opinion of the European Food Safety Authority (EFSA). The investigation during
Leonie Rinke   +3 more
wiley   +1 more source

From quantum groups to genetic mutations

open access: yes, 2003
In the framework of the crystal basis model of the genetic code, where each codon is assigned to an irreducible representation of $U_{q \to 0}(sl(2) \oplus sl(2))$, single base mutation matrices are introduced.
Sciarrino, Antonino
core  

Evolved DNAzymes and Stable Activation Chemistry Enable High‐Efficiency DNA Ligation

open access: yesChemistry – A European Journal, EarlyView.
In vitro selection of pre‐structured DNA libraries and chemical screening of alternative activation groups yielded trans‐acting DNAzymes with faster ligation rates and enhanced DNA substrate stability. The combination of C3S1 DNAzymes and phosphobenzimidazole‐activated DNA substrates provides improved DNA ligation performance, offering promise for ...
Connor Nurmi   +3 more
wiley   +1 more source

Purine and carbohydrate availability drive Enterococcus faecalis fitness during wound and urinary tract infections

open access: yesmBio
Enterococcus faecalis is commonly isolated from a variety of wound types. Despite its prevalence, the pathogenic mechanisms of E. faecalis during wound infection are poorly understood. Using a mouse wound infection model, we performed in vivo E. faecalis
Casandra Ai Zhu Tan   +11 more
doaj   +1 more source

Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells

open access: yesChemistry – A European Journal, EarlyView.
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu   +5 more
wiley   +1 more source

Editorial: The role of astrocyte signalling pathways in ageing-induced neurodegenerative pathologies

open access: yesFrontiers in Physiology, 2022
Nady Braidy   +7 more
doaj   +1 more source

E. coli genetically modified for purine nucleobase release promotes butyrate generation and colonic wound healing during DSS insult

open access: yesGut Microbes
The gut microbiota transforms energy stored as undigestible carbohydrates into a remarkable number of metabolites that fuel intestinal bacterial communities and the host tissue.
J. Scott Lee   +7 more
doaj   +1 more source

The Purine‐Nucleotide Cycle [PDF]

open access: bronze, 1980
Juan J. Aragón, John M. Lowenstein
openalex   +1 more source

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