Results 151 to 160 of about 36,659 (205)

Connective tissue disease‐associated interstitial lung disease: an approach to treatment amidst an expanding evidence base

open access: yesInternal Medicine Journal, EarlyView.
ABSTRACT Connective tissue disease‐associated interstitial lung disease (CTD‐ILD) comprises a heterogenous group of conditions characterised by immune‐mediated fibro‐inflammatory pulmonary injury. Although the disease course is variable, CTD‐ILD can progress to respiratory failure and thus has a profound impact on morbidity and mortality.
Michael Hong   +2 more
wiley   +1 more source

Hyperuricaemia in type 1 Gaucher disease: is uric acid a biomarker for disease severity?

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Elevated serum uric acid (SUA) levels were observed in Gaucher disease type 1 (GD1) patients followed for two decades in northern Israel. There are no previous reports regarding hyperuricaemia in GD1 patients. Aims We aimed to evaluate the frequency of hyperuricaemia in GD1 patients and its correlation to disease severity ...
Zufit Hexner‐Erlichman   +4 more
wiley   +1 more source

Impact of body mass index on the association between kidney function and insulin resistance in diabetic and nondiabetic populations

open access: yesJournal of Diabetes Investigation, EarlyView.
In diabetes with overweight/obesity, eGFR was negatively linearly associated with HOMA‐IR, and creatinine was positively linearly associated with HOMA‐IR. In non‐diabetes with overweight/obesity, the relationship between eGFR and HOMA‐IR was L‐shaped, and the relationship between uric acid and HOMA‐IR was inverted L‐shaped.
Ruo Zhang   +4 more
wiley   +1 more source

Mind the GAPS: Glia associated with psychological stress

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank   +4 more
wiley   +1 more source

Metabolomic Profiles of Oral Rinse Samples to Distinguish Severe Periodontitis Patients From Non‐Periodontitis Controls

open access: yesJournal of Periodontal Research, EarlyView.
Metabolomic fingerprints analyzed from oral rinses are able to distinguish between severe periodontitis (stage III/IV) patients and non‐periodontitis controls. ABSTRACT Aims To explore the potential of metabolomic profiles of oral rinse samples to distinguish between patients with severe periodontitis (stage III/IV) and non‐periodontitis controls. This
Madeline X. F. Kosho   +4 more
wiley   +1 more source

Matching maternal and paternal experiences underpin molecular thermal acclimation

open access: yesMolecular Ecology, EarlyView.
Abstract The environment experienced by one generation has the potential to affect the subsequent one through non‐genetic inheritance of parental effects. Since both mothers and fathers can influence their offspring, questions arise regarding how the maternal, paternal and offspring experiences integrate into the resulting phenotype.
L. C. Bonzi   +5 more
wiley   +1 more source

Expression patterns of melanin‐related genes are linked to crypsis and conspicuousness in a pumpkin toadlet

open access: yesMolecular Ecology, EarlyView.
Abstract Colour signals play pivotal roles in different communication systems, and the evolution of these characters has been associated with behavioural ecology, integumentary production processes and perceptual mechanisms of the species involved. Here, we present the first insight into the molecular and histological basis of skin colour polymorphism ...
Juliane P. C. Monteiro   +7 more
wiley   +1 more source

Old Doubts From a New Perspective: Oral Versus Subcutaneous Methotrexate

open access: yes
International Journal of Dermatology, EarlyView.
Laura Kiss, Rolland Gyulai
wiley   +1 more source

The biosynthesis of the purines [PDF]

open access: possibleErgebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1959
Of the many problems which confront the biologist in his understanding of the operations of the cell, the synthesis of biologically important substances is now the most amenable to solution. It has been the domain of the biochemist to probe into the integrated cellular system by dissembling its enzymatic machinery as a means of studying the complex ...
John M. Buchanan, Standish C. Hartman
openaire   +2 more sources

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