Results 151 to 160 of about 53,051 (335)

Diazonium Salts in Visible Light Photocatalysis – a Focused Overview of their Application in Continuous Flow Synthesis

ChemPhotoChem, EarlyView.
The combination of continuous flow technology and visible light photocatalysis has been used to improve the safety and productivity of reactions with diazonium salts as reactive intermediates. This approach has proven to be a reliable method for various organic synthesis routes with diazonium salts under mild and well‐defined conditions.
Christoph Deckers, Thomas H. Rehm
wiley   +1 more source

Thymoquinone induces apoptosis in temozolomide‐resistant glioblastoma cells via the p38 mitogen‐activated protein kinase signaling pathway

Environmental Toxicology, Volume 38, Issue 1, Page 90-100, January 2023., 2023
Abstract Temozolomide (TMZ) can cross the blood‐brain barrier (BBB) and deliver methyl groups to the purine (guanine) bases of DNA, leading to mispairing during DNA replication and subsequent cell death. However, increased expression of the repair enzyme methyl guanine methyltransferase (MGMT), which removes methyl groups from purine bases, counteracts
Ai Mai, Shu‐Wen Ye, Jia‐Yu Tu, Jun Gao, Zhan‐Fang Kang, Qian‐Ming Yao, Wei‐Jen Ting   +6 more
wiley   +1 more source

BIOSYNTHESIS OF THE PURINES

, 1956
Standish C. Hartman, Bruce Levenberg, John M. Buchanan   +2 more
openalex   +2 more sources

Nitrogen-Centered Radicals Derived from Azidonucleosides

Molecules
Azido-modified nucleosides have been extensively explored as substrates for click chemistry and the metabolic labeling of DNA and RNA. These compounds are also of interest as precursors for further synthetic elaboration and as therapeutic agents.
Yahaira Reyes, Amitava Adhikary, Stanislaw F. Wnuk   +2 more
doaj   +1 more source

Ultra-rapid, Quantitative, Label-free Antibiotic Susceptibility Testing via Optically Detected Purine Metabolites [PDF]

arXiv
There is an urgent need for the development of novel and truly rapid (equal or less than 1 hour) antibiotic susceptibility testing (AST) platforms in order to provide best antimicrobial prescribing practices and to help reduce the increasing global threat of antibiotic resistance.
arxiv  

Feeding Experiments with Deficiencies in the Amino-acid supply: Arginine and Histidine as possible Precursors of Purines [PDF]

, 1916
H. Ackroyd, Frederick Gowland Hopkins
openalex   +1 more source

Diversity and determinants of bitterness, astringency, and fat content in cultivated Nacional and native Amazonian cocoa accessions from Ecuador

The Plant Genome, Volume 15, Issue 4, December 2022., 2022
Abstract Cocoa (Theobroma cacao L.) is the only tree that can produce cocoa. Cocoa beans are highly sought after by chocolate makers to produce chocolate. Cocoa can be fine aromatic, characterized by floral and fruity notes, or it can be described as standard cocoa with a more pronounced cocoa aroma and bitterness.
Kelly Colonges, Edward Seguine, Alejandra Saltos, Fabrice Davrieux, Jérôme Minier, Juan‐Carlos Jimenez, Marie‐Christine Lahon, Darío Calderon, Cristian Subia, Ignacio Sotomayor, Fabián Fernández, Olivier Fouet, Bénédicte Rhoné, Xavier Argout, Marc Lebrun, Pierre Costet, Claire Lanaud, Renaud Boulanger, Rey Gastón Loor Solorzano   +18 more
wiley   +1 more source

The Digestibility and Absorption of the Calories, Proteins, Purines, Fat and Calcium in Wholemeal Wheaten Bread [PDF]

, 1948
R. A. McCance, C. M. Walsham
openalex   +1 more source

Analytical and Pharmacological Characterization of 1‐(Furan‐2‐Carbonyl)‐LSD (1F‐LSD) and Comparison With 1‐(Thiophene‐2‐Carbonyl)‐LSD (1T‐LSD)

Drug Testing and Analysis, EarlyView.
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt, Pierce V. Kavanagh, Sarah Gare, Simon P. Elliott, Alexander Stratford, Adam L. Halberstadt   +5 more
wiley   +1 more source

Effects of Dimenhydrinate on Motor Behavior and Vascular Function: Possible Implications for the Field of Sports

Drug Testing and Analysis, EarlyView.
Regarding cardiovascular effects, DMH decreased vascular reactivity to phenylephrine and acetylcholine. We observed that the combination of DPH and 8‐Cl‐T was identified as the responsible for increasing blood pressure and heart rate in the biological model used.
Jazmín Flores‐Monroy, Diana Ramírez‐Hernández, Diego Lezama‐Martínez, Benjamín Velasco‐Bejarano   +3 more
wiley   +1 more source