Results 181 to 190 of about 53,976 (309)

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

Aging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang, Xiaojie Liu, Hairong Lian, Yanchao Chai, Yang Zhou, Dongqi Kan, Jilong Ren, Cui Han, Jiaxin Yang   +8 more
wiley   +1 more source

When the host senses the microbiota's metabolism - the interplay between food and microbiota in C. elegans. [PDF]

FEBS J
Gomes JE.
europepmc   +1 more source

GLYCINE AS A PRECURSOR OF PURINES IN YEAST

, 1948
Richard Abrams, E. Hammarsten, David Shemin   +2 more
openalex   +1 more source

The micro‐determination of purine nitrogen in urine¹ [PDF]

, 1939
T. Raekallio
openalex   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Phosphorylation of nucleosides by P-N bond species generated from prebiotic reduced phosphorus sources. [PDF]

Commun Chem
Gull M, Cruz HA, Krishnamurthy R, Pasek MA.   +3 more
europepmc   +1 more source

The structure of pyrimidines and purines. II. A determination of the structure of adenine hydrochloride by X-ray methods

, 1948
J. M. Broomhead
openalex   +1 more source

Stimulation of the Respiration of Chlorella Vulgaris by Purines and Purine Analogues [PDF]

Plant Physiology, 1960
Michael K. Bach, J. Fellig
openaire   +2 more sources

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li, Jie Liu, Jie Ju, Xiaoling Peng, Wei Zhao, Jihao Ren, Xiaoqian Jia, Jihong Wang, Ye Tu, Feng Gao   +9 more
wiley   +1 more source

Purine metabolism rewiring improves glioblastoma susceptibility to temozolomide treatment. [PDF]

Cell Death Dis
D'Aprile S, Denaro S, Torrisi F, Longhitano L, Giallongo S, Giallongo C, Bontempi V, Bucolo C, Drago F, Mione MC, Li Volti G, Potokar M, Jorgačevski J, Zorec R, Tibullo D, Amorini AM, Vicario N, Parenti R.   +17 more
europepmc   +1 more source