Results 231 to 240 of about 99,040 (285)

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress. [PDF]

open access: yesClin Cancer Res
Yu J   +16 more
europepmc   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

open access: yesThe FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan   +4 more
wiley   +1 more source

Temozolomide-Derived AIC Is Incorporated into Purine Synthesis in Glioblastoma. [PDF]

open access: yesChem Res Toxicol
Sowers ML   +9 more
europepmc   +1 more source

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

open access: yesJournal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson   +2 more
wiley   +1 more source

DNA base pairs: the effect of the aromatic ring on the strength of the Watson-Crick hydrogen bonding.

open access: yesOrg Biomol Chem
Nieuwland C   +7 more
europepmc   +1 more source

When chemistry meets taxonomy: Studying glycolipidic chemomarkers in pelagic Sargassum spp. (Phaeophyceae) using molecular networking

open access: yesJournal of Phycology, EarlyView.
Abstract To chemically differentiate the three pelagic Sargassum morphotypes co‐occurring in floating rafts and drifting across the Atlantic Ocean before stranding on West African, Caribbean, and Atlantic Mexican coastlines, we conducted an investigation of their metabolomic profiles.
Charlotte Nirma   +5 more
wiley   +1 more source

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