Results 231 to 240 of about 98,235 (335)

Unraveling unbreakable hairpins: characterizing RNA secondary structures that are persistent after dinucleotide shuffling. [PDF]

RNA
Pratt AA, Hendrix DA.
europepmc   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, EarlyView.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Creation of strain – producer of bacterial purine nucleoside phosphorylase fused with human annexin A5

, 2020
A. B. Bulatovski, А. И. Зинченко   +1 more
openalex   +2 more sources

Purin [PDF]

, 2019
openaire   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

DNA base pairs: the effect of the aromatic ring on the strength of the Watson-Crick hydrogen bonding.

Org Biomol Chem
Nieuwland C, van Well MJ, Guillaumes L, de Vey Mestdagh A, Dekker L, Nieuweboer C, Simon S, Fonseca Guerra C.   +7 more
europepmc   +1 more source

Can the origin of biosynthetic routes be explained by a Frankenstein's monster-like spontaneous assembly of prebiotic reactants? [PDF]

Philos Trans R Soc Lond B Biol Sci
Negrón-Mendoza A, Hernández-Morales R, Lazcano A.   +2 more
europepmc   +1 more source

Inhibition of histamine release by purine and pyrimidine derivatives

, 1982
Kazuhiro Shimamura, Masahiro Nishibori, Hiroshi Yokoyama, Kohji Tsutsumi, Kiyomi Saeki   +4 more
openalex   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Quick screening for <i>Brucella</i> virulence genes with the Bat-VFDB: <i>Brucella</i> addition to the Virulence Factor DataBase. [PDF]

Microbiol Resour Announc
Kampfraath AA, Koomen J, Dijkstra T, Koets A, van den Esker MH.   +4 more
europepmc   +1 more source