Results 271 to 280 of about 53,976 (309)
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New England Journal of Medicine, 1976
To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
David W. Martin +3 more
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To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
David W. Martin +3 more
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New England Journal of Medicine, 1970
"The biochemistry of uric acid and its relation to gout" was recently (1963) reviewed in a series of articles that appeared in the Medical Progress section of the Journal.1 In this series the bioch...
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"The biochemistry of uric acid and its relation to gout" was recently (1963) reviewed in a series of articles that appeared in the Medical Progress section of the Journal.1 In this series the bioch...
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2003
The activation of adenosine A1, A2 andA3 receptors can protect neurones against damage generated by mechanical or hypoxic/ischaemic insults as well as excitotoxins. A1 receptors are probably effective by suppressing transmitter release and producing neuronal hyperpolarisation.
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The activation of adenosine A1, A2 andA3 receptors can protect neurones against damage generated by mechanical or hypoxic/ischaemic insults as well as excitotoxins. A1 receptors are probably effective by suppressing transmitter release and producing neuronal hyperpolarisation.
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ChemInform Abstract: Synthesis of Certain Alkenyl Purines and Purine Analogues.
ChemInform, 1995AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
T. S. Rao, G. R. Revankar
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Journal of Cellular and Comparative Physiology, 1951
GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring, has been completely separated from 5-amino-4-imidazolecarboxamide ribotide transformylase (3). The latter enzyme is responsible for the incorporation of formate carbon into position 2 of the purine ring.
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GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring, has been completely separated from 5-amino-4-imidazolecarboxamide ribotide transformylase (3). The latter enzyme is responsible for the incorporation of formate carbon into position 2 of the purine ring.
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Life Sciences, 1987
The fact that purine nucleotides and nucleosides are so important in normal cellular functions makes their analysis complicated. In order to measure tissue levels, samples have to be very rapidly fixed. Measurement in blood is complicated by the risk of releasing purine nucleotides during the sampling procedure and by the possibility of very rapid ...
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The fact that purine nucleotides and nucleosides are so important in normal cellular functions makes their analysis complicated. In order to measure tissue levels, samples have to be very rapidly fixed. Measurement in blood is complicated by the risk of releasing purine nucleotides during the sampling procedure and by the possibility of very rapid ...
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Theoretical studies on the purine radical induced purine–purine type intrastrand cross-links
Organic & Biomolecular Chemistry, 2019Purine-type radicals can attack their 3′/5′ flanking purine deoxynucleosides forming the purine–purine type DNA intrastrand cross-links.
Shoushan Wang +6 more
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1987
Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
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Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
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Inhibition of Lipid Peroxidation by Purines and Analogues of Purine
1995The importance of oxygen radicals in tissue injury is widely recognized(1). Mutation, cancer, inflammation, and ageing are thought to be caused by oxygen radicals. It has also been confirmed that lipids are peroxidized by oxygen radicals leading to the damaging effects on cellular constituents. Mickel & Horbar(2) reported that peroxidized lipids affect
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1991
Publisher Summary This chapter discusses the important novel basic chemistry of the purine system, and interesting new compounds obtained by established methods. The basic chemistry of the purine system is established for a very long time. Many new procedures for the synthesis of purine derivatives and many thousands of novel nucleoside analogues have
G. Mackenzie, D.F. Ewing
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Publisher Summary This chapter discusses the important novel basic chemistry of the purine system, and interesting new compounds obtained by established methods. The basic chemistry of the purine system is established for a very long time. Many new procedures for the synthesis of purine derivatives and many thousands of novel nucleoside analogues have
G. Mackenzie, D.F. Ewing
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