Results 271 to 280 of about 99,040 (285)

Nitrite supplementation alleviates cerebrovascular dysfunction in chronically stressed mice, but cognitive decline remains

Experimental Physiology, EarlyView.
Abstract This study aimed to determine whether sodium nitrite supplementation prevented chronic stress‐induced cerebrovascular dysfunction and cognitive decline. We hypothesize that nitrite supplementation will prevent the oxidative environment and cerebrovascular dysfunction associated with chronic stress and maintain cognitive health.
Emily Burrage, Tyler Coblentz, Saina S. Prabhu, Nicole M. Eminhizer, Ryan Childers, Randall W. Bryner, Sara E. Lewis, Brooke A. Maxwell, Evan R. DeVallance, Eric E. Kelley, Paul D. Chantler   +10 more
wiley   +1 more source

P2X7 regulates ependymo-radial glial cell proliferation in adult Danio rerio following spinal cord injury

Biology Open
Eva E. Stefanova, Julian Vincent T. Dychiao, Mavis C. Chinn, Matin Borhani, Angela L. Scott   +4 more
doaj   +1 more source

Recent advances in the synthesis, reaction, and bio-evaluation potential of purines as precursor pharmacophores in chemical reactions: a review. [PDF]

RSC Adv
Ragab A.
europepmc   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Purine Molecular Interactions Determine Anisotropic Shape of Zebrafish Biogenic Crystals. [PDF]

Small Methods
Rothkegel J, Kaufmann S, Wilsch-Bräuninger M, Lopes C, Mateus R.   +4 more
europepmc   +1 more source

The critical role of methylenetetrahydrofolate dehydrogenases in immune regulation and auto-immunity. [PDF]

J Inflamm (Lond)
Bunyard P, Makrecka-Kuka M, McMillan L.
europepmc   +1 more source

Impact of (poly)phenol-rich dietary sources on DNA damage: insights from human intervention studies using the Comet assay - a review and perspective. [PDF]

Br J Nutr
Milev M, Roglev B, Kondeva Rogleva M, Georgieva M, Miloshev G, Ruskovska T.   +5 more
europepmc   +1 more source

<i>Lactiplantibacillus plantarum</i> WLPL04 from Human Breast Milk Attenuates Hyperuricemia via Coordinated Purine Salvage Pathway, Renal Transporter Regulation, and Gut Microbiota Remodeling. [PDF]

Nutrients
Wei M, Hu Y, Zhang Z, Qiu L, Tao X, Wei H.   +5 more
europepmc   +1 more source

Genome-scale metabolic modelling of trimethoprim’s mode of action reveals free ATP salvaged to restore purine pool

Carter C, Singh D, Wain J, Langridge GC.
europepmc   +1 more source

The <i>Agrobacterium fabrum</i> efflux pump PecM is produced in response to the plant exudate 4-hydroxybenzaldehyde to avoid disruption of central metabolism. [PDF]

J Bacteriol
Ghosh A, Grove A.
europepmc   +1 more source