Results 21 to 30 of about 53,051 (335)
In the context of our SAR study concerning 6BrCaQ analogues as C-terminal Hsp90 inhibitors, we designed and synthesized a novel series of 3-(heteroaryl)quinolin-2(1H), of types 3, 4, and 5, as a novel class of analogues.
Enrique L. Larghi+5 more
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Magnetic circular dichroism within the Algebraic Diagrammatic Construction scheme of the polarisation propagator up to third order [PDF]
We present an implementation of the B term of Magnetic Circular Dichroism within the Algebraic Diagrammatic Construction (ADC) scheme of the polarization propagator and its Intermediate State Representation. As illustrative results, the MCD spectra of the ADC variants ADC(2), ADC(2)-x and ADC(3) of the molecular systems uracil, 2-thiouracil, 4 ...
arxiv +1 more source
The aim of this study was to evaluate production performance, carcass characteristics and nutritive value of meat of rabbits reared under the 2 prevailing feeding strategies in Uruguay.
Gustavo Capra+6 more
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Existen pruebas estandarizadas para evaluar la calidad de las semillas y para ensayos de biomonitoreo ambiental, las cuales utilizan indicadores que permiten establecer la sensibilidad de diversas especies a condiciones ambientales, aunque los momentos ...
Lorna Ileana Carbó+4 more
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A Generalization of the Auslander-Reiten Conjecture for the Bounded Derived Category [PDF]
We study the bounded derived category $\D^b(\Rmod)$ of a left Noetherian ring $R$. We give a version of the Generalized Auslander-Reiten Conjecture for $\D^b(\Rmod)$ that is equivalent to the classical statement for the module category and is preserved under derived equivalence.
arxiv +1 more source
Chronic infections with Staphylococcus aureus such as septicemia, osteomyelitis, endocarditis, and biofilm infections are difficult to treat because of persisters.
Rebecca Yee+4 more
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2,6-Bis[4-(4-butylphenyl)-1H-1,2,3-triazol-1-yl]-9-dodecyl-9H-purine
Target 2,6-bis[4-(4-butylphenyl)-1H-1,2,3-triazol-1-yl]-9-dodecyl-9H-purine has been prepared via a Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction between 2,6-diazido-9-dodecyl-9H-purine and 4-n-butyl(phenylacetylene) in a 29% yield. The
Andrejs Šišuļins+3 more
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Scientific investigations of the Nobel prize winner Emil Fischer as a launching pad for the development of biochemistry: a brief overview [PDF]
Modern biochemistry and molecular biology would be impossible without discoveries in related fields of science. This paper aims to outline briefly the main stages of scientific activity of a Nobel Prize winner 1902 – German chemist Hermann Emil Fischer ...
T. V. Danylova, S. V. Komisarenko
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Background: Although imatinib is a well-established first-line drug for treating a vast majority of gastrointestinal stromal tumours (GIST), GISTs acquire secondary resistance during therapy.
Szymon Macioszek+8 more
doaj
Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA.
Raquel Buj, Katherine M. Aird
doaj +1 more source