Results 41 to 50 of about 50,189 (192)

Genetic Screen Reveals the Role of Purine Metabolism in Staphylococcus aureus Persistence to Rifampicin

open access: yesAntibiotics, 2015
Chronic infections with Staphylococcus aureus such as septicemia, osteomyelitis, endocarditis, and biofilm infections are difficult to treat because of persisters.
Rebecca Yee   +4 more
doaj   +1 more source

2,6-Bis[4-(4-butylphenyl)-1H-1,2,3-triazol-1-yl]-9-dodecyl-9H-purine

open access: yesMolbank, 2019
Target 2,6-bis[4-(4-butylphenyl)-1H-1,2,3-triazol-1-yl]-9-dodecyl-9H-purine has been prepared via a Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction between 2,6-diazido-9-dodecyl-9H-purine and 4-n-butyl(phenylacetylene) in a 29% yield. The
Andrejs Šišuļins   +3 more
doaj   +1 more source

Substituted Purines as High-Affinity Histamine H3 Receptor Ligands

open access: yesPharmaceuticals, 2022
Continuing with our program to obtain new histamine H3 receptor (H3R) ligands, in this work we present the synthesis, H3R affinity and in silico studies of a series of eight new synthetically accessible purine derivatives.
Christian Espinosa-Bustos   +7 more
doaj   +1 more source

Meat quality of rabbits reared with two different feeding strategies: with or without fresh alfalfa ad libitum

open access: yesWorld Rabbit Science, 2013
The aim of this study was to evaluate production performance, carcass characteristics and nutritive value of meat of rabbits reared under the 2 prevailing feeding strategies in Uruguay.
Gustavo Capra   +6 more
doaj   +1 more source

RNA Catabolites Contribute to the Nitrogen Pool and Support Growth Recovery of Wheat

open access: yesFrontiers in Plant Science, 2018
Turn-over of RNA and catabolism of nucleotides releases one to four ammonia molecules; the released nutrients being reassimilated into primary metabolism.
Vanessa Jane Melino   +8 more
doaj   +1 more source

Synthesis of Indole Derivatives via Aryl Triazole Ring-Opening and Subsequent Cyclization

open access: yesMolecules
A metal-free two-step synthetic approach for obtaining indole derivatives from aryl triazole fragment-containing compounds has been developed. In the first step, the Dimroth equilibrium, followed by nitrogen extrusion, Wolff rearrangement, and amine ...
Aleksejs Burcevs   +4 more
doaj   +1 more source

Optimized MS/MS settings of purines and related metabolites.

open access: yes, 2019
Optimized MS/MS settings of purines and related metabolites.
Sven F. Garbade (3700849)   +9 more
core   +1 more source

Substrate identification of putative NCS1 and NCS2 nucleobase transporters in Pseudomonas aeruginosa

open access: yesmBio
Pseudomonas aeruginosa is an opportunistic pathogen that can salvage nucleobases from the environment to conserve nutrients that would otherwise be spent on de novo nucleotide biosynthesis.
Corey Kennelly, Arthur Prindle
doaj   +1 more source

A new model organism for studying the catabolism of pyrimidines and purines.

open access: yes, 1998
Saccharomyces kluyveri, pyrimidines, purines ...
Paracchini, Silvia   +6 more
core   +1 more source

Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease

open access: yesFrontiers in Endocrinology, 2018
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA.
Raquel Buj, Katherine M. Aird
doaj   +1 more source

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