Synthesis of Indole Derivatives via Aryl Triazole Ring-Opening and Subsequent Cyclization
MoleculesA metal-free two-step synthetic approach for obtaining indole derivatives from aryl triazole fragment-containing compounds has been developed. In the first step, the Dimroth equilibrium, followed by nitrogen extrusion, Wolff rearrangement, and amine ...
Aleksejs Burcevs +4 more
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Infrared absorption spectra of a series of 2, 6-diamino and 2-amino-6hydroxy-8-choroalkyl purines [PDF]
, 2003 8-haloalky purines were synthesized and infrared analysis (IR) carried out on them. The syntheses as well as the ill analyses are reported. The purines synthesized and studied include (i) 2,6-diamin-8-Chloromethyl purines, (ii) 2, 6-diamin-8-chlorethyl
I. M., Ejimadu
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Purine-Furan and Purine-Thiophene Conjugates [PDF]
Molbank, 2018 Furyl and thienyl moieties were introduced into a purine structure to elevate its fluorescence properties, while a trityl group was used to increase the amorphous properties of the purine compounds. The title compounds were prepared by a sequence involving a Mitsunobu, a SNAr and a Suzuki–Miyaura reaction and their photophysical properties were studied.
Zigfrīds Kapilinskis +2 more
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Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]
, 1986 The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R. +5 more
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A TDDFT study of the excited states of DNA bases and their assemblies [PDF]
, 2006 We present a detailed study of the optical absorption spectra of DNA bases and base pairs, carried out by means of time dependent density functional theory.
Di Felice, R. +3 more
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Parallel purine‐pyrimidine‐purine triplex: experimental evidence for existence [PDF]
FEBS Letters, 1995 Oligonucleotides 5′‐d(CT)5‐L‐d(AG)5‐L‐d(GA)5‐3′ and 5′‐d(GA)5‐L‐d(TC)5‐L‐d(GA)5‐3′ [L = pO(CH2CH2O)3p] were studied by thermal denaturation, chemical modification and binding of fluorescent dyes. Both oligonucleotides are shown to fold back on itself twice forming at pH 7 a sufficiently stable triplex ether with antiparallel‐oriented oligopurine ...
Shchyolkina, Anna K. +6 more
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Substrate identification of putative NCS1 and NCS2 nucleobase transporters in Pseudomonas aeruginosa
mBioPseudomonas aeruginosa is an opportunistic pathogen that can salvage nucleobases from the environment to conserve nutrients that would otherwise be spent on de novo nucleotide biosynthesis.
Corey Kennelly, Arthur Prindle
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Absorption of pyrimidines, purines and nucleosides by Li, Na, Mg, and Ca montmorillonite /clay organic studies 12/ [PDF]
Absorption of purines, pyrimidines, and nucleoside in aqueous solution by montmorillionite occurring as cation exchange ...
Brindley, G. W. +2 more
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Robust signatures in the current-voltage characteristics of DNA molecules oriented between two graphene nanoribbon electrodes [PDF]
, 2012 In this work we numerically calculate the electric current through three kinds of DNA sequences (telomeric, \lambda-DNA, and p53-DNA) described by different heuristic models.
Alberts B +10 more
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Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
Frontiers in Endocrinology, 2018 The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA.
Raquel Buj, Katherine M. Aird
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