Results 201 to 210 of about 80,189 (259)

Enhanced mGluR1 function causes motor deficits and region-specific Purkinje cell dysfunction

Ibrahim MF, Boyanova S, Cheng YC, Ligneul C, Bains RS, Lerch JP, Mann E, Oliver PL, Becker EBE.   +8 more
europepmc   +1 more source

Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue. [PDF]

Cell Rep Methods
Bartelt LC, Fakhri M, Adamek G, Trybus M, Samelak-Czajka A, Jackowiak P, Fiszer A, Lowe CB, La Spada AR, Switonski PM.   +9 more
europepmc   +1 more source

Purkinje cell hyperexcitability and depressive-like behavior in mice lacking erg3 (ether-à-go-go-related gene) K⁺ channel subunits. [PDF]

Sci Adv
Schwarz JR, Freitag S, Pechmann Y, Hermans-Borgmeyer I, Wagner W, Wagner W, Hornig S, Kneussel M.   +7 more
europepmc   +1 more source

Purkinje cell intrinsic activity shapes cerebellar development and function

Osório C, White JJ, Solé PT, Mandemaker N, Olivero F, Kirwan F, de Winter F, Regolo E, Fiocchi FR, Serra I, Tjon S, Ozgur Z, van den Hout MC, van Ijcken WFJ, López-Bendito G, Badura A, Lim L, van Woerden G, Schonewille M.   +18 more
europepmc   +1 more source

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Cardiac Purkinje cells

Heart Rhythm, 2010
Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling.
Penelope A, Boyden, Masanori, Hirose, Wen, Dun   +2 more
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The purkinje cell cilium

The Anatomical Record, 1969
AbstractIn the course of ultrastructural studies on the cerebellar cortex of young rats a cilium was found in some Purkinje cells. The shaft, which is 1800 to 2000 ÅR thick, has an internal portion inside the cell body and an external one projecting into the neuropile. The basal body is consistently located near the Golgi apparatus.
Manuel P. Del Cerro, Ray S. Snider, Mary Lou Oster   +2 more
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Cardiac Purkinje cells in culture

Journal of Molecular and Cellular Cardiology, 1983
Purkinje cells from false tendons of young rabbits, pigs and fetal lambs were dispersed by the action of collagenase and elastase and grown in culture for up to 14 days. Immunofluorescent staining with fluorescein-labelled antibodies to cardiac myosin and tropomyosin demonstrated cross-banding and/or a diffuse positive stain in Purkinje cells between 3
Canale, E, Campbell, JH, Campbell, GR
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Aging of cerebellar Purkinje cells

Cell and Tissue Research, 2010
Cerebellar Purkinje cells (PCs), the sole output neurons in the cerebellar cortex, play an important role in the cerebellar circuit. PCs appear to be rather sensitive to aging, exhibiting significant changes in both morphology and function during senescence.
Changzheng, Zhang, Qingfeng, Zhu, Tianmiao, Hua   +2 more
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Anatomy embroiders function in Purkinje cells

The Lancet Neurology, 2021
The anatomy of the human cerebellar Purkinje cell, as captured by Ramón y Cajal in a drawing, inspired the spectacular cover embroidery by Lisa Stoneman (Roanoke College, Roanoke, VA, USA) in the October issue of The Lancet Neurology. 1 Like contemporary confocal microscopy images do, this anatomical representation also raises fascinating questions ...
Attwell, David, Mehta, Arpan R
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Purkinje Cell Transplants inShakerMutant Rats with Hereditary Purkinje Cell Degeneration and Ataxia

Experimental Neurology, 1998
Shaker mutant rats are characterized by the adult-onset degeneration of cerebellar anterior lobe Purkinje cells and temporally correlated development of ataxia and tremor. Normal E-13 Purkinje cells were transplanted into the anterior cerebellum in adult shaker mutant rats to study donor/host interactions in an animal with adult-onset ...
D L, Tolbert, J, Heckroth
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